Results 121 to 130 of about 208,281 (313)
Chronic myeloid leukemia (CML) is caused by the Philadelphia (Ph+) chromosome carrying the BCR-ABL oncogene, a constitutively active tyrosine kinase. The discovery of imatinib represents a major success story in the treatment against CML.
Liuya Wei+13 more
doaj
Persistence of chronic myelocytic leukemia despite deletion of rearranged bcr/c-abl sequences in blast crisis. [PDF]
Claus R. Bartram+4 more
openalex +1 more source
The Development of Indo‐Iranian Voiced Fricatives
Abstract The development of voiced sibilants is a long‐standing puzzle in Indo‐Iranian historical phonology. In Vedic, all voiced sibilants are lost from the system, but the details of this loss are complex and subject to debate. The most intriguing development concerns the word‐final ‐aḥ to ‐o in sandhi.
Gašper Beguš
wiley +1 more source
Health Equity Benefits All Communities (Including White Ones)
Policy Points Despite the goal of “all communities thriving,” health equity–focused scientists and advocates have inadvertently made it easier for those “opposed to equity” to falsely convince many White communities that health equity–promoting policies and programs do not benefit them or their health.
PHILIP M. ALBERTI
wiley +1 more source
A membrane-associated, carbohydrate-modified form of the v-abl protein that cannot be phosphorylated in vivo or in vitro [PDF]
Susan M. Watanabe+2 more
openalex +1 more source
Abstract Farm delinquency is linked to many negative indicators of farm survival, including increased risk of bankruptcy and farm failure. Minority farmers and ranchers (MFR) have been found to exhibit higher rates of delinquency on U.S. Department of Agriculture (USDA) Farm Service Agency (FSA) loans compared to their non‐Hispanic White male ...
Lawson Connor+3 more
wiley +1 more source
Modeling of an Atmospheric-Boundary-Layer Profile in Support of Experiments in the NASA Langley Transonic Dynamics Tunnel [PDF]
This paper presents the results of the Computational Fluid Dynamics (CFD) analyses to model two atmospheric-boundary-layer (ABL) profiles inside the NASA Langley Research Center Transonic Dynamics Tunnel (TDT). The CFD models include tunnel walls and all
Chwalowski, Pawel, Ivanco, Thomas G.
core +1 more source
Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl. [PDF]
John L. Cleveland+4 more
openalex +1 more source
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert+10 more
wiley +1 more source