Results 151 to 160 of about 217,258 (295)

c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration [PDF]

, 2023
Alexis Martínez, Cristian M. Lamaizon, Cristian Valls, Fabien Llambi, Nancy Leal, Patrick Fitzgerald, Cliff Guy, Marcin M. Kamiński, Nibaldo C. Inestrosa, Brigitte van Zundert, Gonzalo I. Cancino, Andrés E. Dulcey, Silvana Zanlungo, Juan Marugán, Claudio Hetz, Douglas R. Green, Alejandra Álvarez   +16 more
openalex   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev, Nagore Ambrosio, Cheryl Somani, Elena Figuero, Lior Shapira, Janet Davies   +5 more
wiley   +1 more source

Supplementary Figure 1 from Antitumor Activity of Saracatinib (AZD0530), a c-Src/Abl Kinase Inhibitor, Alone or in Combination with Chemotherapeutic Agents in Gastric Cancer

, 2023
Hyun-Jin Nam, Seock‐Ah Im, Do‐Youn Oh, Paul Elvin, Hwang‐Phill Kim, Young‐Kwang Yoon, Ahrum Min, Sang‐Hyun Song, Sae‐Won Han, Tae‐You Kim, Yung‐Jue Bang   +10 more
openalex   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Air‐Polishing Versus Ultrasonic Instrumentation for Nonsurgical Treatment of Peri‐Implantitis: A Randomized Clinical Trial

Journal of Periodontal Research, EarlyView.
This RCT offers a nuanced understanding of nonsurgical peri‐implantitis management (air polishing with erythritol versus ultrasonic instrumentation, in combination with systemic metronidazole), integrating both clinical and patient‐centered outcomes. The results showed that the ultrasonic instrumentation reduced probing depth and bleeding on probing ...
Ana Isabel Moreira, Tiago Caetano, Francisco Correia, Honorato Ribeiro‐Vidal, Ricardo Faria Almeida   +4 more
wiley   +1 more source

Computational Analysis of the Binding Specificity of Gleevec to Abl, c-Kit, Lck, and c-Src Tyrosine Kinases

, 2013
Yen-Lin Lin, Benoı̂t Roux
openalex   +1 more source

Philadelphia chromosome‐positive acute lymphoblastic leukaemia in children and adolescents: A changing treatment landscape and a methodological challenge

British Journal of Haematology, EarlyView.
Adriana Balduzzi, Maria Grazia Valsecchi, Thai Hoa Tran, Jan Zuna, Veronica Leoni, Gunnar Cario, Grazia Fazio, Virginie Gandemer, Sarah K. Tasian, Inge M. van der Sluis, Nicolò Peccatori, Rosanna Parasole, Stefania Monterisi, Mignon L. Loh, Meenakshi Devidas, Stephen P. Hunger, John A. Kairalla, Paola De Lorenzo, Lewis B. Silverman, Andrea Biondi   +19 more
wiley   +1 more source

USP10 in Neurological Disorders: Mechanistic Insights and Emerging Therapeutic Strategies

Annals of the New York Academy of Sciences, EarlyView.
USP10 is a deubiquitinating enzyme that affects neurological diseases through multiple mechanisms, including the accumulation of toxic proteins, autophagy, and immune responses. In this review, we discuss the structure and characteristics of USP10 and summarize the role of USP10 in neurological disorders.
Celemuge, Hongying Sun, Jia Zhang, Yang Yang, Jian Mao, Cheliger   +5 more
wiley   +1 more source

Can antimicrobial blue light contribute to resistance development? Genome-wide analysis revealed aBL-protective genes in Escherichia coli

Microbiology Spectrum
Antimicrobial blue light (aBL) is a promising non-antibiotic approach to fighting multidrug-resistant bacteria. However, the complete mechanism of aBL action is not fully understood yet.
Beata Kruszewska-Naczk, Mariusz Grinholc, Krzysztof Waleron, Julia Elisabeth Bandow, Aleksandra Rapacka-Zdończyk   +4 more
doaj   +1 more source

Inhibition of activated STAT5 in Bcr/Abl expressing leukemia cells with new pimozide derivatives

, 2014
Riccardo Rondanin, Daniele Simoni, Romeo Romagnoli, Riccardo Baruchello, Paolo Marchetti, Cristiana Costantini, Sara Fochi, Giacomo Padroni, Stefania Grimaudo, Rosaria Maria Pipitone, Maria Meli, Manlio Tolomeo   +11 more
openalex   +2 more sources