Results 171 to 180 of about 217,258 (295)
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani +5 more
wiley +1 more source
Role of Interfacial Water Molecules in Proline-rich Ligand Recognition by the Src Homology 3 Domain of Abl [PDF]
, 2009 Andrés Palencia +4 more
openalex +1 more source
Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer
International Journal of Cancer, Volume 158, Issue 6, Page 1464-1480, 15 March 2026.Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley +1 more source
Single amino acid–based PROTACs trigger degradation of the oncogenic kinase BCR–ABL in chronic myeloid leukemia (CML) [PDF]
, 2023 Jianchao Zhang +5 more
openalex +1 more source
Oral Administration of Freeze‐Dried Lactobacillus zeae Alleviates Periodontitis by Affecting the Oral and Intestinal Flora [PDF]
Food Sci NutrFirst, probiotic strain Lactobacillus zeae N165 with oral antibacterial activity, autoaggregation ability and coaggregation ability was screened through in vitro experiments. Then, in vivo efficacy evaluation was conducted on this strain, and a mouse model was used to verify its ameliorative effect on periodontitis.
Liang Q +5 more
europepmc +2 more sources
Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.We analyzed the behavior of GPR143 gene‐deficient mice. GPR143‐KO mice displayed a mixed psychiatric phenotype. GPR143 may play a role in mesolimbic and mesocortical functions underlying sensory gating, reward, social hierarchy, cognition, and emotional regulation. ABSTRACT GPR143, originally identified as the gene product of ocular albinism 1 (OA1), a
Yoshio Goshima +9 more
wiley +1 more source
Phosphorylation of Dok1 by Abl family kinases inhibits CrkI transforming activity
, 2014 K Y Ng +4 more
openalex +1 more source
Analysis of domain-specific function reveals significant plasticity in BCR-ABL signaling [PDF]
, 2022 Tomáš Gregor +8 more
openalex +1 more source
Journal of Applied Entomology, Volume 150, Issue 2, Page 243-253, March 2026.ABSTRACT Previous studies on Cydia pomonella eggs have demonstrated reliable egg adhesion to the leaves and fruits of various apple cultivars. In contrast to biological substrates, this study is focused on standardised synthetic substrates to measure egg pull‐off forces and determine adhesive strength, allowing for an unbiased comparison with other ...
Loris Al Bitar +3 more
wiley +1 more source