Results 171 to 180 of about 210,001 (312)

The v-abl tyrosine kinase negatively regulates NF-kappa B/Rel factors and blocks kappa gene transcription in pre-B lymphocytes.

, 1994
Christopher A. Klug, S J Gerety, Purnank Shah, Y Y Chen, Nancy R. Rice, Naomi Rosenberg, Harinder Singh   +6 more
openalex   +1 more source

Tyrosine Phosphorylation of RNA Polymerase II Carboxyl-terminal Domain by the Abl-related Gene Product [PDF]

, 1997
Rathinasamy Baskaran, Gary G. Chiang, Tami H. Mysliwiec, Gary D. Kruh, Jean Y. J. Wang   +4 more
openalex   +1 more source

A computational dynamic model of combination treatment for type II inhibitors with asciminib

Protein Science, Volume 34, Issue 8, August 2025.
Abstract Despite continuous strides forward in drug development, resistance to treatment looms large in the battle against cancer as well as communicable diseases. Chronic myeloid leukemia (CML) is treated with targeted therapy and treatment is personalized when resistance arises.
J. Roadnight Sheehan, Astrid S. de Wijn, Ran Friedman   +2 more
wiley   +1 more source

Leukemia initiated by hemopoietic stem cells expressing the v-abl oncogene.

, 1991
S W Chung, P. Wong, Helen G. Durkin, Y S Wu, J. Petersen   +4 more
openalex   +1 more source

Dissecting NK Cell Development Using a Novel Alymphoid Mouse Model: Investigating the Role of the c-abl Proto-Oncogene in Murine NK Cell Differentiation [PDF]

, 1999
Francesco Colucci, Claire Soudais, Eleftheria Rosmaraki, Lesley Vanes, Victor L. J. Tybulewicz, James P. Di Santo   +5 more
openalex   +1 more source

Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid‐beta accumulation, neurofibrillary tangles, and neuroinflammation. The therapeutic efficacy of traditional single‐target drugs has been
Md Saad Hossain, Md Hamed Hussain
wiley   +1 more source

Anterior bone loss after anterior cervical discectomy and fusion: influence factors and its impact on surgical outcomes. [PDF]

BMC Musculoskelet Disord
Zong R, Liu CY, Jin YZ, Peng ZH, He JB, Wu TK, Liu H, Yu AY.   +7 more
europepmc   +1 more source

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.

, 1991
Alexander J. Muller, Judy Young, Ann Marie Pendergast, Mark Pondel, NR Landau, Dan R. Littman, Owen N. Witte   +6 more
openalex   +1 more source

Binding of A/T-rich DNA by Three High Mobility Group-like Domains in c-Abl Tyrosine Kinase [PDF]

, 1996
Yongjie Miao, Jean Y. J. Wang
openalex   +1 more source

Quality of life for braille users: A scoping review

Review of Education, Volume 13, Issue 2, August 2025.
Abstract Quality of life (QoL) encompasses well‐being, life satisfaction and happiness, enabling individuals to lead meaningful lives. Literacy, the ability to read and write, is essential for inclusion in education, employment and society. For people with blindness or low vision (BLV), braille is a critical tool for accessing literacy.
Aasha Rose, Melissa Fanshawe, Georgina Barton, Melissa Cain   +3 more
wiley   +1 more source