Results 181 to 190 of about 217,258 (295)

Identification of a <i>Musashi2</i> translocation as a novel oncogene in myeloid leukemia. [PDF]

Elife
Spinler K, Hamilton M, Bajaj J, Shima Y, Diaz E, Kritzik M, Reya T.   +6 more
europepmc   +1 more source

P660: NEXT-GENERATION SEQUENCING (NGS) FOR DETECTING BCR::ABL-INDEPENDENT MUTATIONS IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA WITH RESISTANCE TO TYROSINE KINASE INHIBITOR TREATMENT

, 2023
Daria Kustova, Anna Kirienko, Ekaterina Motyko, Vasily Shuvaev, Elizaveta Efremova, Elena Morozova, Sergey Sidorkevich, Irina Martynkevich   +7 more
openalex   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Advances in Targeting BCR-ABL^T315I Mutation with Imatinib Derivatives and Hybrid Anti-Leukemic Molecules. [PDF]

Molecules
Tuzikiewicz A, Wawrzyniak W, Kutner A, Żołek T.   +3 more
europepmc   +1 more source

Sharp commutator estimates of all order for Coulomb and Riesz modulated energies

Communications on Pure and Applied Mathematics, Volume 79, Issue 2, Page 207-292, February 2026.
Abstract We prove functional inequalities in any dimension controlling the iterated derivatives along a transport of the Coulomb or super‐Coulomb Riesz modulated energy in terms of the modulated energy itself. This modulated energy was introduced by the second author and collaborators in the study of mean‐field limits and statistical mechanics of ...
Matthew Rosenzweig, Sylvia Serfaty
wiley   +1 more source

The Role of c-Abl in Alzheimer's Disease: Guilty or not Guilty? [PDF]

Cell Mol Neurobiol
Li W, Wang X, Liu J, Chen Y.
europepmc   +1 more source

Assessment of Pharmacokinetic Drug Interaction of Asciminib with Atorvastatin in Healthy Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.
Abstract Asciminib is the first BCR::ABL1 inhibitor that Specifically Targets the ABL Myristoyl Pocket (STAMP) in patients with chronic myeloid leukemia. This phase 1, two‐treatment‐period, drug‐drug interaction study evaluated the effect of steady‐state asciminib on the pharmacokinetics of atorvastatin.
Matthias Hoch, Wendy Weis, Felix Huth, Seshulatha Jamalapuram, Michelle Quinlan, Amarnath Bandaru, Suleyman Eralp Bellibas, Asmae Mirkou, Shruti Kapoor, Shefali Kakar   +9 more
wiley   +1 more source

Fusion oncoproteins orchestrate tumorigenesis and sustain malignant progression via a positive feedback mechanism. [PDF]

Cell Biosci
Ying W, Wang X, Yu J, Wang J, He Q, Yang B, Chen Y, Ying M.   +7 more
europepmc   +1 more source

The Application of Iron Nanoparticles Green‐Synthesized by Coptis chinensis Leaf Aqueous Extract in Reducing the TNF‐α and IL1‐β Inflammatory Cytokines in the Rat Periodontal Model

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Treatment of periodontitis by the iron nanoparticles. ABSTRACT The study purpose was to examine how the green‐synthesized iron nanoparticles (FeNPs) made from Coptis chinensis extract affected the TNF‐α and IL1‐β gingival levels in the rat periodontal model. The extract from C. chinensis was utilized as a green reducing agent and a great stabilizer for
Jialing Wu, Xinjie Gao, Ruiqi Li
wiley   +1 more source

Effect of novel antimicrobial blue light-emitting optical fiber on vancomycin-resistant <i>Enterococcus faecium</i> and carbapenemase-producing <i>Klebsiella pneumoniae</i>. [PDF]

J Bone Jt Infect
Goh MH, Körber-Irrgang B, Hederick LL, Rabiner RA, Wisplinghoff H, Chen AF, Jazmati N, Lozano-Calderon SA.   +7 more
europepmc   +1 more source