Results 191 to 200 of about 62,826 (275)

Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase [PDF]

open access: green, 1998
Salme Taagepera   +6 more
openalex   +1 more source

Multi‐Omic Analysis of Glutamate Excitotoxicity in Primary Neuronal Cultures

open access: yesJournal of Neurochemistry, Volume 169, Issue 6, June 2025.
Our study on rat neuron cells found 250 μM glutamate to be toxic, causing neuron death. We identified genes in pathways linked to apoptosis, neuron plasticity, and cell signaling, along with proteins regulating the cell cycle and tumor proliferation.
Jennifer H. Nguyen   +13 more
wiley   +1 more source

enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties. [PDF]

open access: gold, 1995
Frank B. Gertler   +6 more
openalex   +1 more source

Adult stakeholders' perspectives on supporting or undermining the mental health of sexual and gender minoritised adolescents

open access: yesPsychology and Psychotherapy: Theory, Research and Practice, Volume 98, Issue 2, Page 256-274, June 2025.
Abstract Objectives To explore adult stakeholders' perspectives on what supports or undermines the mental health of sexual and gender minoritised adolescents (SGMA) in everyday life in order to better understand how to foster supportive psychosocial environments for SGMA. Design Descriptive qualitative study design, using framework analysis.
Rajvinder Samra   +5 more
wiley   +1 more source

Bcr/Abl associated leukemogenesis in bcr null mutant mice

open access: bronze, 1998
Jan Willem Voncken   +3 more
openalex   +1 more source

Novel clinical trial designs emerging from the molecular reclassification of cancer

open access: yesCA: A Cancer Journal for Clinicians, Volume 75, Issue 3, Page 243-267, May/June 2025.
Abstract Next‐generation sequencing has revealed the disruptive reality that advanced/metastatic cancers have complex and individually distinct genomic landscapes, necessitating a rethinking of treatment strategies and clinical trial designs. Indeed, the molecular reclassification of cancer suggests that it is the molecular underpinnings of the disease,
Mina Nikanjam   +4 more
wiley   +1 more source

Memory-like Natural Killer Cell and CD19 Antibody-Based Immunotherapy in Combination with Tyrosine Kinase Inhibition Has Antitumor Effects against Ph(-like) Acute Lymphoblastic Leukemia. [PDF]

open access: yesCancer Immunol Res
Eskandarian Z   +16 more
europepmc   +1 more source

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