Journal of Clinical Periodontology, EarlyView.ABSTRACT Background This Consensus Workshop dealt with diagnostic methodologies in the context of surveillance, screening, assessment of stage and grade, prognosis, monitoring and prediction of periodontal status. Several elements provided the impetus for the workshop, including the limited quality of available research on diagnostic tests, the rapid ...
David Herrera +67 more
wiley +1 more source
Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive Leukemias
Advances in Hematology, 2015 BCR-ABL-mediated leukemias, either Chronic Myeloid Leukemia (CML) or Philadelphia positive Acute Lymphoblastic Leukemia (ALL), are the paradigm of targeted molecular therapy of cancer due to the impressive clinical responses obtained with BCR-ABL ...
Alessandro Morotti +6 more
doaj +1 more source
Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis
Cell Communication and Signaling, 2019 Background Deregulated c-Abl activity has been intensively studied in a variety of solid tumors and leukemia. The class-I carcinogen Helicobacter pylori (Hp) activates the non-receptor tyrosine kinase c-Abl to phosphorylate the oncoprotein cytotoxin ...
Gernot Posselt +13 more
doaj +1 more source
Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc: conditional regulation of c-myc transcription by temperature-sensitive v-abl. [PDF]
, 1989 John L. Cleveland +4 more
openalex +1 more source
Journal of Clinical Periodontology, EarlyView.ABSTRACT Aim There is evidence linking tooth loss with dementia; however, similar findings for periodontitis are inconclusive. Material and Methods We conducted cross‐sectional (N = 4046) and longitudinal analyses (N = 2769) on data from the Health 2000 and 2011 surveys for establishing any associations of periodontal health with baseline cognition, 11‐
Sam Asher +5 more
wiley +1 more source
Molecular Therapy: Oncolytics, 2020 Chronic myeloid leukemia (CML) is caused by the Philadelphia (Ph+) chromosome carrying the BCR-ABL oncogene, a constitutively active tyrosine kinase. The discovery of imatinib represents a major success story in the treatment against CML.
Liuya Wei +13 more
doaj
Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl, and src oncogenes. [PDF]
, 1986 Kevin L. Holmes +3 more
openalex +1 more source
Journal of Oral Rehabilitation, EarlyView.ABSTRACT Background Artificial intelligence (AI) and various subunits of AI such as artificial neural networks (ANN), Convolutional neural networks (CNNs), machine learning (ML), deep learning (DL) and deep neural networks (DNN) are being tried to diagnose and plan treatment for periodontal diseases.
Rupanjan Roy +3 more
wiley +1 more source
Linkage of the tuberous sclerosis locus to a DNA polymorphism detected by v-abl. [PDF]
, 1987 J. M. Connor +4 more
openalex +1 more source
A Survey of the Current Practice for Testing for Neonatal Hypoglycaemia in Aotearoa, New Zealand
Journal of Paediatrics and Child Health, EarlyView.ABSTRACT Aims Neonatal hypoglycaemia is the most common metabolic disturbance in newborns and can lead to brain injury. However, the feasibility of implementing a national recommendation to use accurate testing methods to avoid under‐ and over‐diagnosis depends on current practise, preferences, and resources.
C. M. Ulyatt +4 more
wiley +1 more source