Results 131 to 140 of about 793,672 (364)

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Iatrogenic Tamponade Induced by Torn Catheter Sheath

open access: yesArchives of Clinical and Experimental Surgery, 2014
A 64-year-old man underwent ablation for atrioventricular node reentry tachycardia. After 1 month, he presented to the emergency room with increasing dyspnea, chest pain, and shock secondary to cardiac tamponade.
Manabu Shiraishi   +3 more
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Laser Ablation Modelling: The link between Desorption and Ablation regime [PDF]

open access: yesarXiv, 2004
A new parameterized model for the ablation phenomena is presented. The model describes the three different regimes usually observed, as a function of the laser fluence. The first one corresponds to a vaporization; it takes place at low fluence and it is well described by a typical Arrhenius expression, dependent on the vaporization energy Ev, of the ...
arxiv  

Clinical and Procedural Effects of Transitioning to Contact Force Guided Ablation for Atrial Fibrillation. [PDF]

open access: yes, 2019
Background: A major innovation in atrial fibrillation (AF) ablation has been the introduction of contact force (CF) sensing catheters. Objective: To evaluate procedural and clinical effects of transitioning to CF-guided AF ablation.
Dikdan, Sean J., Frisch, Daniel R.
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Atrial fibrillation and its determinants after radiofrequency ablation of chronic common atrial flutter [PDF]

open access: yes, 2005
Aim. Atrial fibrillation (AFib) is a major clinical issue and its occurrence is the main problem after catheter ablation of atrial flutter. The long-term occurrence of AFib after common atrial flutter ablation is still matter of debate as it may ...
Bortone, Agustin   +7 more
core   +2 more sources

All-optical ion generation for ion trap loading

open access: yes, 2011
We have investigated the all-optical generation of ions by photo-ionisation of atoms generated by pulsed laser ablation. A direct comparison between a resistively heated oven source and pulsed laser ablation is reported.
A. Steane   +28 more
core   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

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