Impact of Extended Use of Ablation Techniques in Cirrhotic Patients with Hepatocellular Carcinoma: A Cost-Effectiveness Analysis. [PDF]
Ramtohul T +15 more
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Enhancement of skin permeability with thermal ablation techniques: concept to commercial products. [PDF]
Parhi R, Mandru A.
europepmc +1 more source
Atrial fibrillation is the most common arrhythmia affecting millions of people globally. The increasingly aging population and those with established cardiovascular risk factors (i.e., diabetes, obesity, hypertension, heart failure, and sleep apnea) are most susceptible to this arrhythmia and its dreaded complications. Although early detection, primary
openaire +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Aortic Regurgitation as a Complication of Electrophysiologic Ablation Techniques: A Narrative Review. [PDF]
Shehata E +5 more
europepmc +1 more source
Endovenous thermal ablation for healing venous ulcers and preventing recurrence. [PDF]
Carradice, D +4 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Implications of RAS Mutations on Oncological Outcomes of Surgical Resection and Thermal Ablation Techniques in the Treatment of Colorectal Liver Metastases. [PDF]
Rhaiem R +4 more
europepmc +1 more source
Embedding of fibre optic sensors within flexible host [PDF]
This work deals with the establishment of a UV polymerisation procedure combined with moulding technology towards the development of a mass production technology for the fabrication of flexible polymers with optical fibres embedded.
Dubruel, Peter +7 more
core

