Results 141 to 150 of about 3,414,706 (323)

Identity, mental health, and ableism in Australian schools: findings from a multi-stakeholder survey

open access: yes
Ableism is a serious problem in schools across Australia and internationally. Our mixed method survey investigated who is impacted by school student experiences of ableism and how they are affected.
Longfellow, L.   +3 more
core   +1 more source

Atmospheres of Ableism: A Phenomenological Exploration of Everyday Encounters

open access: yes
Campbell and Nario-Redmond explain that ableism entails explicit and implicit biases that manifest at every level of social life. At the same time, Taussig describes ableism as the atmosphere we breathe.
Parke, Kelly
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The Myth of Brokenness: Ableism and Anti-Ableism in the Field of Speech-Language Pathology

open access: yes
This Zine investigates the treatment of clients with disabilities within the field of speech-language pathology (SLP). Speech-language pathologists support individuals with communication challenges such as individuals recovering from a stroke, Autistic ...
Sutton, Kieran
core  

Ableism - a problem within occupational therapy? : A general literature review

open access: yes
Purpose: The purpose of this study is to map, analyze and describe current research on the prevalence and expression of ableism within occupational therapy. Method: A general literature review was chosen as the study design.
Lindh, Johanna, Bergdahl, Monika
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Dimensions of Ableism: Educational and Developmental Ability-Expectations

open access: yes, 2015
This paper offers a reflection on results of a case study on inclusive education conducted in Nigeria. It takes up Gregor Wolbring`s (2008, 257) suggestion to look at ability from a broader perspective and thus focuses on the complex relationship between
Biermann, Julia
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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