Results 81 to 90 of about 9,096 (274)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Ableism as transformative practice
, 2014 [Introduction]: There has been an assortment of ways to think about and designate disability and corporeal difference. We are familiar with the biomedical approach and more recent concept of the social model of disability which links the designation ...
Campbell, Fiona Kumari
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Inclusion o'clock—Time embodiment in the experiences of disabled employees [PDF]
This study introduces the concept of “timeism” to examine how ableist assumptions about time and productivity intersect to marginalize disabled workers in organizational contexts.
Georgiadou, Andri, Damianidou, Eleni
core +1 more source
PLoS ONEYouth with disabilities often encounter many challenges in securing employment. Although the common barriers that youth face are well documented, little is known about the experiences of youth who have multiple minoritized identities in finding and ...
Sally Lindsay +2 more
doaj +1 more source
The symbolic intersecting ableism and racism scale
Frontiers in Rehabilitation SciencesIntroductionIntersectionality recognizes and maps the ways oppressions interact and intersect for multiply marginalized people. This framework is a pushing back against the historical approach to discrimination that has taken a “single-axis” view of ...
Carli Friedman
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Zwischen Capabilities und Ableism [PDF]
peer reviewedZusammenfassung In diesem Beitrag diskutieren wir sozialpädagogische Verhältnisse zwischen menschenrechtsorientierter Befähigung und individualistischer Fähigkeitsorientierung mit möglichen exkludierenden Folgen.
PROYER, Michelle, More, Rahel
core +2 more sources
Ableism and Magical Healing in Fantasy
, 2021 Does magical healing in fantasy literature promote a culture of ...
Hatcher, Erin
core +1 more source