Results 101 to 110 of about 9,096 (274)
Research Ethics ReviewThis study critically explores ability expectations in collaborative research with disability communities to highlight ethical consequences and outline an ableism-critical research practice.
Rahel More
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Ableism a zjawisko infrahumanizacji "obcych" [PDF]
, 2016 The purpose of this article is to draw attention to the infrahumanisation phenomenon of Otherness in the context of ableism. In the discussion, a reference is made to the concept of infrahumanisation, explaining what its essence and characteristic ...
Bełza-Gajdzica, Magdalena
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The Symbolic Ableism Scale [PDF]
, 2019 This study validates the Symbolic Ableism Scale (SAS), which examines subtle prejudice. The SAS has four underlying themes: individualism; recognition of continuing discrimination; empathy for disabled people; and, excessive demands.
Carli Friedman & Jessica M Awsumb
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Perceptual filters: Exploring disability and ableism’s cognitive framework
Journal of Family Medicine and Primary CareAbleism, akin to other forms of discrimination such as sexism and racism, is increasingly recognized as a pervasive societal concern directed towards individuals with disabilities.
Abhimanyu Vasudeva +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Atmospheres of Ableism: A Phenomenological Exploration of Everyday Encounters [PDF]
Campbell and Nario-Redmond explain that ableism entails explicit and implicit biases that manifest at every level of social life. At the same time, Taussig describes ableism as the atmosphere we breathe.
Parke, Kelly
core +3 more sources