Artemisinin derivative-containing therapies and abnormal hemoglobin: Do we need to adapt the treatment? [PDF]
Background: Artemisinin-based treatment in malaria patients with abnormal hemoglobin may be ineffective because of their genetic particularity, which could lead to resistance.
Gbessi Eric A. +10 more
doaj +3 more sources
Molecular epidemiological investigation of abnormal hemoglobin in Shaokwan region, southern China
Objectives Shaokwan is one of the inhabitant regions of Hakka population in Guangdong province of southern China. Previous survey has reported that a higher prevalence of abnormal hemoglobin (Hb) in this region.
Hui Yang +5 more
doaj +2 more sources
A Third Abnormal Hemoglobin Associated with Hereditary Hemolytic Anemia [PDF]
Previous work from these Laboratories has established the existence of an abnormal hemoglobin in sickle cell trait and sickle cell anemia and has provided the basis for a theory relating the presence of the abnormal hemoglobin to the clinical pictures in
Harvey A Itano
exaly +1 more source
Hemoglobin bologna (α2β2 61 (E5) Lys → Met) An abnormal human hemoglobin wlth low oxygen affinity
An abnormal human hemoglobin was found in association with β-thalassemia in a hemolysate from an 11-year-old healthy child living in Bologna (northern) Italy). Structural studies demonstrated a previously unreported amino acid substitution, β 61 (E5) Lys
M Marinucci +2 more
exaly +2 more sources
Fructosamine and glycated hemoglobin level in pregnant women with abnormal glucose challenge test
Background and Objective: Gestational diabetes is affected 3-12% of women and occurs at the final stage of second trimester. This study was done to determine the fructosamine and glycated hemoglobin level in pregnant women with abnormal glucose challenge
Bostani Fargoosh P +5 more
doaj +1 more source
A Novel Alpha1‐Variant (HBA1:c.‐35T>C) Complexed With the First Reported Hb M‐Saskatoon in the Chinese Population [PDF]
Background Hemoglobinopathies are genetic disorders characterized by structural or quantitative hemoglobin abnormalities. We report the first documented case globally of a novel alpha1 (α1)‐variant (HBA1:c.‐35T>C) co‐occurring with Hb M‐Saskatoon (HBB:c ...
Yujing Yang +5 more
doaj +2 more sources
The human hemoglobins, with genetically defined inheritance patterns, have shown characteristic polymorphic variation within the Brazilian population, depending on the racial groups of each region. They have appeared under the form of hemoglobin variants
Imperial, Rodrigo E. [UNESP] +8 more
openaire +3 more sources
Anormal Hemoglobinler'in Farklı Hemoglobin Elektroforezleri ile Belirlenmesi
Özet: Genetik hastalıklar içinde önemli bir yere sahip olan anormal hemoglobinler pek çok ülkede önemli bir sağlık sorunu olarak bilinmektedir. Dünya göç ve ticaret yolları üzerinde bulunan Türkiye´de anormal hemoglobinleri belirlemek amacıyla özellikle ...
Azize Güngör +2 more
doaj +1 more source
Unexpected Detection of Abnormal Hemoglobin Variants During Routine HbA1c Analysis by HPLC Technique: Challenges and Opportunities in HbA1c Testing [PDF]
Background: Glycated Hemoglobin A1c (HbA1c) assay is most widely used in diabetic patients for assessing long-term control of glycemia. The presence of hemoglobin variants may be an incidental finding and can interfere with HbA1c measurements. The aim of
Neelam Narsingrao Sreedevi +5 more
doaj +1 more source
"Pseudo-Abnormal" Hemoglobins [PDF]
Abstract Three examples of artefactual "pseudo-abnormal" hemoglobins were observed in the course of starch block electrophoresis analysis of over 400 specimens. In fresh samples from the same patients, these components were no longer demonstrable.
H A, PEARSON, J V, McCOO, S L, LEIKIN
openaire +2 more sources

