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The identification of five rare beta-chain abnormal hemoglobins by high performance liquid chromatographic procedures.

Hemoglobin, 1986
The detection, quantitation, and characterization of five relatively rare beta chain abnormal hemoglobins mainly by high performance liquid chromatographic procedures are described.
J. B. Wilson   +6 more
semanticscholar   +1 more source

Distribution of abnormal hemoglobins and glucose-6-phosphate dehydrogenase variants in 1200 school children of Bahia, Brazil.

American Journal of Physical Anthropology, 1980
School children from Bahia, Brazil were studied for hemoglobin and glucose-6-phosphate dehydrogenase electrophoretic variants. Eighty-nine heterozygotes Hb AS and 41 Hb AC were identified out of 1200 children.
E. Azevêdo   +5 more
semanticscholar   +1 more source

ABNORMAL HEMOGLOBINS: LABORATORY METHODS

Hemoglobin, 2001
Laboratory methods allowing the detection and characterization of hemoglobin variants are reviewed. Protein chemistry techniques such as isoelectrofocusing, electrophoreses under various experimental conditions, cation exchange and reversed phase high performance liquid chromatography, are the most frequently used for the detection of variants.
Josiane Bardakdjian-Michau   +8 more
openaire   +3 more sources

Abnormal hemoglobins found in Guangdong, P.R. China.

Hemoglobin, 1987
(1987). Abnormal Hemoglobins Found in Guangdong, P.R. China. Hemoglobin: Vol. 11, No. 6, pp. 573-579.
P. C. Jen
semanticscholar   +1 more source

Abnormal hemoglobins in the Negroes of Surinam

The American Journal of Medicine, 1958
Abstract 1. 1. A study of the incidence of abnormal hemoglobins among the Djuka population of Surinam revealed an incidence of sickle cell hemoglobin of 15 per cent and an incidence of hemoglobin C of 3 per cent. Two cases interpreted as sickle cell-thalassemia disease indicated the probable presence of the gene for thalassemia in the Djukas. The
Claire Liachowitz   +4 more
openaire   +3 more sources

Detection of two abnormal hemoglobins, Hb Manitoba and Hb G-Coushatta, during analysis of glycohemoglobin (A1c) by high-performance liquid chromatography.

Clinical Chemistry, 1991
This report concerns the detection of two abnormal hemoglobins (Hb), Hb Manitoba and Hb G Coushatta, during analysis for glycohemoglobin (Hb A1c). Blood samples from two diabetic patients, analyzed for Hb A1c by HPLC, were found to contain additional Hb ...
S. Wong, M. Tesanovic, M. Poon
semanticscholar   +1 more source

Evaluation of proficiency in the performance of tests for abnormal hemoglobins.

American Journal of Clinical Pathology, 1974
A hemoglobinopathy proficiency testing program was initiated by the Hematology Section of the Center for Disease Control to evaluate the ability of screening programs to detect abnormal hemoglobins in the United States.
R. M. Schmidt, E. Brosious
semanticscholar   +1 more source

Standardization in Detection of Abnormal Hemoglobins

JAMA, 1973
Seven commercial hemoglobin (Hb) S solubility tests were evaluated to ascertain their specificity, sensitivity, accuracy, and precision when used to determine the presence of S hemoglobin. Two hundred blood specimens, including 97 samples expected to give a positive test (samples containing either Hb S or Hb CHarlem), were tested.
Robert M. Schmidt, Sylvia M. Wilson
openaire   +3 more sources

Normal and Abnormal Human Hemoglobins

1963
Publisher Summary This chapter reviews that spectacular progress has been made in the recognition and study of biological differences between hemoglobin types. Many aspects of variations in hemoglobins such as the worldwide distribution of human hemoglobin types and their epidemiologic implications, animal hemoglobin types, and others have not been ...
openaire   +4 more sources

Hemoglobin and Its Abnormalities

JAMA, 1961
Several years ago, Ingram made the exciting discovery that substitution of one amino acid for another ( valine substituted for glutamic acid) in one of the peptide chains is apparently the only chemical difference between normal and sickle cell hemoglobin.
openaire   +2 more sources

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