Results 71 to 80 of about 1,740,227 (374)

Correlation Between Fecal Microbiota and Corticosteroid Responsiveness in Primary Immune Thrombocytopenia: an Exploratory Study

open access: yesAdvanced Science, EarlyView.
This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu   +38 more
wiley   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

open access: yesAdvanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong   +20 more
wiley   +1 more source

Porotic Hyperostosis in the Eastern Mediterranean [PDF]

open access: yes, 1978
Porotic hyperostosis is bone expansion caused by hypertrophy of blood-forming marrow. It usually affects the skull diploë in adults and the long bones, face, skull vault, and sometimes the trunk in children, often with some thinning and porosity in the ...
Angel, J. Lawrence
core   +1 more source

Clinical complications of G6PD deficiency in Latin American and Caribbean populations : systematic review and implications for malaria elimination programmes [PDF]

open access: yes, 2014
Background: Although G6PDd individuals are generally asymptomatic throughout their life, the clinical burden of this genetic condition includes a range of haematological conditions, including acute haemolytic anaemia (AHA), neonatal jaundice (NNJ) and ...
Bassat, Quique   +9 more
core   +2 more sources

α-Thalassemia impairs the cytoadherence of Plasmodium falciparum-infected erythrocytes. [PDF]

open access: yesPLoS ONE, 2012
α-Thalassemia results from decreased production of α-globin chains that make up part of hemoglobin tetramers (Hb; α(2)β(2)) and affects up to 50% of individuals in some regions of sub-Saharan Africa.
Michael A Krause   +10 more
doaj   +1 more source

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

open access: yesAdvanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

Sickle cell disease status among school adolescents and their tribal community in South Gujarat [PDF]

open access: yes, 2009
Objectives: to create awareness, to screen samples of school adolescents and then to reach their community through them by doing surveillance for sickle cell disease. Design: Field based cross-sectional study. Settings: St Xavier`s high school and Vanraj
Chudasama, Rajesh K   +3 more
core   +1 more source

ANEMIA FALCIFORME EM QUILOMBOLAS: UMA REVISÃO DE LITERATURA [PDF]

open access: yes, 2018
Introduction: Sickle cell disease is a generic term that encompasses a set of hematological disorders linked to structural changes in blood cells, leading to the production of an abnormal hemoglobin called HbS, the 'S' being derived from English sickle ...
Borges, Renan Pires Ferreira   +5 more
core   +2 more sources

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

open access: yesAdvanced Science, EarlyView.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang   +11 more
wiley   +1 more source

Hemoglobin variants with electrophoretic mobility similar to hemoglobin S [PDF]

open access: yes, 2017
9ª Reunião Científica da Sociedade Portuguesa de Medicina Laboratorial, 7-8 abril 2017Hemoglobinopathies are among the most common inherited diseases around the world and are one of the world’s major health problems.
Copeto, Sandra   +8 more
core  

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