Drug-Induced Hematologic Syndromes
Objective. Drugs can induce almost the entire spectrum of hematologic disorders, affecting white cells, red cells, platelets, and the coagulation system.
David M. Mintzer+2 more
doaj +2 more sources
Metabolic and electrolyte abnormalities as risk factors in drug-induced long QT syndrome
Drug-induced long QT syndrome (diLQTS) is the phenomenon by which the administration of drugs causes prolongation of cardiac repolarisation and leads to an increased risk of the ventricular tachycardia known as torsades de pointes (TdP). In most cases of
Clifford TeBay, A. Hill, M. Windley
semanticscholar +1 more source
Idiosyncratic drug-induced liver injury (DILI) is a type of hepatic injury caused by an uncommon drug adverse reaction that can develop to conditions spanning from asymptomatic liver laboratory abnormalities to acute liver failure (ALF) and death.
Marina Villanueva-Paz+6 more
semanticscholar +1 more source
Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects
Oxidative stress is a key pathological feature implicated in both acute and chronic liver diseases, including drug-induced liver injury (DILI).
Yonela Ntamo+9 more
semanticscholar +1 more source
Liver Enzyme Abnormalities and Associated Risk Factors in HIV Patients on Efavirenz-Based HAART with or without Tuberculosis Co-Infection in Tanzania. [PDF]
To investigate the timing, incidence, clinical presentation, pharmacokinetics and pharmacogenetic predictors for antiretroviral and anti-tuberculosis drug induced liver injury (DILI) in HIV patients with or without TB co-infection.
A Habtewold+62 more
core +10 more sources
Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): adverse effects approach [PDF]
: BACKGROUND: The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR), designed to evaluate the effectiveness of a six-months regimen, assessed the adverse effects caused by the drugs.
Rossilene Conceição da Silva Cruz+8 more
doaj +2 more sources
Possibly drug-induced palpable migratory arciform erythema [PDF]
Palpable migratory arciform erythema is an entity of unknown etiology, with few published cases in the literature. The clinical and histopathological features of this disease are difficult to be distinguished from those of Jessner’s lymphocytic ...
Fernando Luiz Teixeira Dantas+5 more
doaj +1 more source
Phenotype standardization for drug-induced kidney disease. [PDF]
Drug-induced kidney disease is a frequent cause of renal dysfunction; however, there are no standards to identify and characterize the spectrum of these disorders.
Awdishu, Linda+8 more
core +7 more sources
Drug-Induced Liver Injury and COVID-19 Infection: The Rules Remain the Same
The pandemic infection by coronavirus 2019 (COVID-19) that spreading from China is generating a tremendous flow of information and one emerging point is the frequent association of COVID-19 infection with liver abnormalities. Studies from China showed an
A. Olry+5 more
semanticscholar +1 more source
Effect of nitrofen in the final stages of development of the diaphragm muscle in rats [PDF]
PURPOSE: To evaluate the expression of myosin in muscle fibers of the diaphragm in experimental congenital diaphragmatic hernia (CDH). METHODS: Fetuses of pregnant rats were divided into four groups: External Control (EC), composed of non-manipulated ...
Frances Lilian Lanhellas Gonçalves+6 more
doaj +1 more source