Results 31 to 40 of about 293,712 (302)

Erupción fija por luz solar, una serie de 13 casos en Bogotá, Colombia

Actas Dermo-Sifiliográficas
Resumen: Desde 1975 se han publicado algunos casos que asocian la radiación ultravioleta como un desencadenante de erupciones cutáneas fijas (erupción o exantema fijo por luz solar o síndrome de fotosensibilidad localizada de amplio espectro ...
M.C. Valbuena, C. Bravo, M.C. Rolón-Cadena   +2 more
doaj   +1 more source

Negative effects of abuse of laxatives in medical practice

Gastroenterologìa, 2018
The abuse of laxatives is a disorder characterized by an incomprehensible and changing range of gastrointestinal, electrolytic and acid-base abnormalities that can lead to both the onset of chronic diseases and fatalities.
Yu.M. Stepanov, O.N. Vlasova, M.V. Stoikevych   +2 more
doaj   +1 more source

Study of Cytogenetic Effects of Cimetidine Drug in White mice (Mus musculus) [PDF]

Engineering and Technology Journal, 2017
This study aimed to detect the cytogenetic effects of Cimetidine drug, which used in the treatment of gastric ulceration, reflux oesophagitis through the tests (mitotic index of Somatic cells in bone marrow and spleen, frequency of micronuclei ...
T.G. Mohamed, A.A. Mohamed
doaj   +1 more source

Evaluation of state and trait biomarkers in healthy volunteers for the development of novel drug treatments in schizophrenia. [PDF]

, 2011
Antipsychotic drugs are the mainstay of treatment for schizophrenia but they have little effect on core negative symptoms or cognitive impairment. To meet the deficiencies of current treatments, novel potential compounds are emerging from preclinical ...
Wilkinson, Lawrence Stephen, Deakin, Bill; id_orcid, Simon Killcross, Ettinger, Ulrich, Ettinger, U., Emma Barkus, Bill Deakin, Killcross, Simon, Roiser, Jonathan P., Ivan Koychev, Deakin, B., Ulrich Ettinger, Wilkinson, Lawrence, Deakin, Bill, Jonathan P Roiser, Killcross, Andrew Simon, Barkus, Emma, Roiser, J. P., Barkus, E., Koychev, Ivan, Koychev, I., Lawrence Wilkinson   +21 more
core   +1 more source

Drug-induced liver injury by glecaprevir/pibrentasvir treatment for chronic hepatitis C infection: a systematic review and meta-analysis

, 2021
Background: Glecaprevir/pibrentasvir (G/P; 300 mg/120 mg) is a new direct-acting antiviral (DAA) that exhibits anti-hepatitis C virus (HCV) pan-genotype (GT) activity for 8, 12, or 16 weeks. However, the U.S.
Chung-Yu Chen (628946), Chia-Lung Shih (3878995), Wei-Liang Hung (11889723), Hsuan-Yu Hung (11411726)   +3 more
core   +1 more source

Abnormal lymphocyte function is secondary to drug-induced autoimmunity. [PDF]

Annals of the Rheumatic Diseases, 1976
Abnormal lymphocyte function has been frequently reported in patients with connective tissue diseases but its significance has been uncertain. Sequential studies of lymphocyte function were carried out in patients receiving the beta-adrenergic blocking drug practolol (Eraldin) both before and during the development of autoimmune complications.
S, Pugh, B, Pelton, E B, Raftery, A M, Denman   +3 more
openaire   +2 more sources

Mechanisms of termination and prevention of atrial fibrillation by drug therapy [PDF]

, 2011
Atrial fibrillation (AF) is a disorder of the rhythm of electrical activation of the cardiac atria. It is the most common cardiac arrhythmia, has multiple aetiologies, and increases the risk of death from stroke.
Smith, G.L., A.J. Workman, Rankin, A.C., A.C. Rankin, Workman, A.J., G.L. Smith   +5 more
core   +1 more source

Drug-induced Physeal Abnormalities in Preclinical Toxicity Studies [PDF]

Toxicologic Pathology, 2017
Most toxic physeal changes are characterized microscopically by altered chondrocyte development, proliferation, or maturation in the growth plate and eventually result in disordered appositional bone growth. Many therapeutic drugs directly or indirectly target proteins involved in chondrocytic differentiation and maturation pathways, so toxic physeal ...
openaire   +2 more sources

Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database [PDF]

, 2013
Background: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US ...
MORETTI, Ugo, De Ponti F., Sturkenboom, M, Sturkenboom, M.C.J.M. (Miriam), De Ponti, F, Behr, E.R. (Elijah), Koci A, Spina, E, Sturkenboom M, Ariola Koci, Poluzzi E, Spina E, Raschi, E. (Emanuel), Ponti, F. (Fabrizio) de, Ugo Moretti, Spina, E. (Edoardo), Poluzzi, E, POLUZZI, ELISABETTA, Koci, A. (Ariola), Behr ER, Koci, A, Elijah R. Behr, Elisabetta Poluzzi, Poluzzi, E. (Elisabetta), Sturkenboom, MCJM, Moretti, U. (Ugo), Fabrizio De Ponti, KOCI, ARIOLA, Moretti, U, Emanuel Raschi, Raschi, E, Miriam Sturkenboom, DE PONTI, FABRIZIO, Moretti U, RASCHI, EMANUEL, Behr, ER, Raschi E, Edoardo Spina   +37 more
core   +1 more source

Torsadogenic risk of antipsychotics : combining adverse event reports with drug utilization data across Europe [PDF]

, 2013
Antipsychotics (APs) have been associated with risk of torsade de Pointes (TdP). This has important public health implications. Therefore, (a) we exploited the public FDA Adverse Event Reporting System (FAERS) to characterize their torsadogenic profile; (
Barbui, Corrado, Sturkenboom, Miriam, Barbui Corrado, Marija Kalaba (487415), Miriam Sturkenboom (408749), Barbui, C. (Corrado), Corrado Barbui, Kalaba M, Sturkenboom M, Fabrizio De Ponti (487418), Godman, Brian, Ariola Koci, Raschi, E. (Emanuel), Ponti, F. (Fabrizio) de, Poluzzi Elisabetta, Koci, A. (Ariola), Bjorn Wettermark, Elisabetta Poluzzi, Moretti, U. (Ugo), Miriam Sturkenboom, Godman Brian, Koci Ariola, Bennie, Marion, Brian Godman (487412), Godman B, Moretti U, Moretti Ugo, Koci, Ariola, De Ponti Fabrizio, Godman, B. (Brian), Sturkenboom Miriam, Wettermark B, Sturkenboom, M.C.J.M. (Miriam), Marija Kalaba, Emanuel Raschi (487410), Marion Bennie, Raschi Emanuel, Brian Godman, Kalaba, M. (Marija), Bennie Marion, Wettermark Bjorn, Raschi, Emanuel, Poluzzi, Elisabetta, Ugo Moretti, Elisabetta Poluzzi (487411), De Ponti, Fabrizio, Alfonso Carvajal, Marion Bennie (487416), Ugo Moretti (487414), Ariola Koci (487413), Moretti, Ugo, Wettermark, B. (Bjorn), Kalaba Marija, Poluzzi, E. (Elisabetta), Barbui C, Wettermark, Bjorn, Fabrizio De Ponti, Corrado Barbui (242747), Emanuel Raschi, Kalaba, Marija, Bennie, M. (Marion), Bennie M, Bjorn Wettermark (487417)   +62 more
core   +1 more source