Antipsychotics and Torsadogenic Risk: Signals Emerging from the US FDA Adverse Event Reporting System Database [PDF]
Background: Drug-induced torsades de pointes (TdP) and related clinical entities represent a current regulatory and clinical burden. Objective: As part of the FP7 ARITMO (Arrhythmogenic Potential of Drugs) project, we explored the publicly available US ...
A Bate +53 more
core +4 more sources
Drug Exposure During Pregnancy: A Case-Control Study from a Primary Care Database
Objective: Drug exposure during pregnancy is frequent, even more during first trimester as pregnant women might not be aware of their condition. We used available electronic health records (EHRs) to describe the use of medications during the first ...
Ainhoa Gomez-Lumbreras +6 more
doaj +3 more sources
EFFECT OF LONG TERM ADMINISTRATION OF CARROT ROOTS (Daucus carota) ON SOME CYTOGENETIC PARAMETERS IN WHITE MICE [PDF]
The effect of long term administration of carrot roots (2 months) on some cytogenetic parameters in bone marrow cells of white mice was studied , these included , mitotic index (MI) , micronuclei formation (Mn ) , and chromosomal aberrations (Ch .
Ilham A. Khalaf
doaj +1 more source
Childhood maltreatment and amygdala connectivity in methamphetamine dependence: a pilot study. [PDF]
IntroductionChildhood maltreatment, a well-known risk factor for the development of substance abuse disorders, is associated with functional and structural abnormalities in the adult brain, particularly in the limbic system.
Dean, Andy C +3 more
core +2 more sources
A case report: retigabine induced oral mucosal dyspigmentation of the hard palate [PDF]
Background Dyspigmentation of the oral mucosa has a multitude of aetiological causes. Retigabine, a new antiepileptic drug, has the potential side effect of inducing a blue/purple pigmentation of the oral mucosa in addition to the skin, lips, nails and ...
Beacher, Nicholas G. +2 more
core +1 more source
International Veterinary Epilepsy Task Force Consensus Proposal: Diagnostic approach to epilepsy in dogs [PDF]
This article outlines the consensus proposal on diagnosis of epilepsy in dogs by the International Veterinary Epilepsy Task Force. The aim of this consensus proposal is to improve consistency in the diagnosis of epilepsy in the clinical and research ...
A Pákozdy +59 more
core +8 more sources
Metabolic and electrolyte abnormalities as risk factors in drug-induced long QT syndrome [PDF]
AbstractDrug-induced long QT syndrome (diLQTS) is the phenomenon by which the administration of drugs causes prolongation of cardiac repolarisation and leads to an increased risk of the ventricular tachycardia known as torsades de pointes (TdP). In most cases of diLQTS, the primary molecular target is the human ether-à-go-go-related gene protein (hERG)
Clifford TeBay +2 more
openaire +2 more sources
Interventions for neurocognitive dysfunction [PDF]
Purpose of review: To evaluate current barriers to HIV cure strategies and interventions for neurocognitive dysfunction with a particular focus on recent advancements over the last three years. Recent findings: Optimal anti-retroviral therapy (ART) poses
Brew, B, Ellero, J, Lubomski, M
core +2 more sources
Erupción fija por luz solar, una serie de 13 casos en Bogotá, Colombia
Resumen: Desde 1975 se han publicado algunos casos que asocian la radiación ultravioleta como un desencadenante de erupciones cutáneas fijas (erupción o exantema fijo por luz solar o síndrome de fotosensibilidad localizada de amplio espectro ...
M.C. Valbuena +2 more
doaj +1 more source
Negative effects of abuse of laxatives in medical practice
The abuse of laxatives is a disorder characterized by an incomprehensible and changing range of gastrointestinal, electrolytic and acid-base abnormalities that can lead to both the onset of chronic diseases and fatalities.
Yu.M. Stepanov +2 more
doaj +1 more source

