Results 41 to 50 of about 450,317 (308)

Study of Cytogenetic Effects of Cimetidine Drug in White mice (Mus musculus) [PDF]

Engineering and Technology Journal, 2017
This study aimed to detect the cytogenetic effects of Cimetidine drug, which used in the treatment of gastric ulceration, reflux oesophagitis through the tests (mitotic index of Somatic cells in bone marrow and spleen, frequency of micronuclei ...
T.G. Mohamed, A.A. Mohamed
doaj   +1 more source

Maladaptive plasticity in levodopa-induced dyskinesias and tardive dyskinesias: old and new insights on the effects of dopamine receptor pharmacology. [PDF]

, 2014
Maladaptive plasticity can be defined as behavioral loss or even development of disease symptoms resulting from aberrant plasticity changes in the human brain.
Ahmed, Ananth, Aron, Aron, Baldessarini, Breakefield, Brooks, Byl, Calabresi, Calabresi, Carta, Casey, Casey, Castrén, Cenci, Cenci, Cerasa, Cerasa, Cerasa, Cerasa, Cerasa, Clarke, Crow, Crow, de la Fuente-Fernandez, de la Fuente-Fernandez, Fahn, Ganos, Gottwald, Heckers, Jankovic, Jellinger, Jenner, Kishore, Kishore, Koch, Koch, Koch, Li, Marsden, McEwen, Morgante, Nambu, Obeso, Pakkenberg, Peralta, Picconi, Quartarone, Rascol, Rylander, Salgado-Pineda, Sawada, Sgambato-Faure, Sigwald, Spencer, Teo, Vernon, Vernon, Zesiewicz   +58 more
core   +2 more sources

Abnormal lymphocyte function is secondary to drug-induced autoimmunity. [PDF]

Annals of the Rheumatic Diseases, 1976
Abnormal lymphocyte function has been frequently reported in patients with connective tissue diseases but its significance has been uncertain. Sequential studies of lymphocyte function were carried out in patients receiving the beta-adrenergic blocking drug practolol (Eraldin) both before and during the development of autoimmune complications.
S, Pugh, B, Pelton, E B, Raftery, A M, Denman   +3 more
openaire   +2 more sources

Diphenylhydantoin (Dilantin) gingival hyperplasia: Drug-induced abnormality of connective tissue [PDF]

Proceedings of the National Academy of Sciences, 1976
Various degrees of gingival overgrowth may occur in individuals taking diphenylhydantoin, a drug used widely in the treatment of epilepsy. The tissue overgrowth is made up predominantly of collagen, and may therefore be a useful model for analysis of fibrosis and some other connective tissue abnormalities.
T M, Hassell, R C, Page, A S, Narayanan, C G, Cooper   +3 more
openaire   +3 more sources

Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer [PDF]

, 2019
Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics ...
Ceelen, Wim, De Clercq, Kaat, De Wever, Olivier, Descamps, Benedicte, Hoorens, Anne, Vermeulen, An, Vervaet, Chris, Xie, Feifan   +7 more
core   +2 more sources

Drug-induced Physeal Abnormalities in Preclinical Toxicity Studies [PDF]

Toxicologic Pathology, 2017
Most toxic physeal changes are characterized microscopically by altered chondrocyte development, proliferation, or maturation in the growth plate and eventually result in disordered appositional bone growth. Many therapeutic drugs directly or indirectly target proteins involved in chondrocytic differentiation and maturation pathways, so toxic physeal ...
openaire   +2 more sources

Evaluation of T-wave morphology parameters in drug-induced repolarization abnormalities [PDF]

2013 2nd International Conference on Advances in Biomedical Engineering, 2013
This study evaluates the predictive values of T-wave morphology parameters reflecting the repolarization changes by beat to beat calculation of parameters using different mathematical tools to identify additional markers sensitive to the variation induced by drug in the surface of the electrocardiogram.
Khodor, Nadine, Carrault, Guy, Amoud, Hassan, Khalil, Mohamad, L'Hostis, Philippe, Hernandez, Alfredo   +5 more
openaire   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Indigenous Herbal Drug (Tinospora Cordifolia) Induced Liver Injury: A Case Report [PDF]

Bengal Physician Journal
Drug-induced liver injury (DILI) is a condition characterized by acute or chronic liver damage following the use of hepatotoxic drugs. It can be classified based on clinical presentation (hepatocellular, cholestasis, or mixed), mechanism of ...
Sounak Kumar Roy, Muniruddin SK, Subham Mondal, Sandipan Mukherjee, Santa Subhra Chatterjee   +4 more
doaj   +1 more source

Modeling neurocognitive and neurobiological recovery in addiction [PDF]

, 2019
This book focuses on "what to know" and "how to apply" information, prioritizing novel principles and delineating cutting-edge assessment, phenotyping and treatment ...
Abé, Agartz, Aharonovich, Almeida, Anderson, Bae, Bates, Bernardin, Blaine, Block, Bolla, Brody, Buhler, Cardenas, Cardenas, Cavazos-Rehg, Chang, Chang, Charlet, Crews, Crews, de Wit, Demirakca, Di Sclafani, Dlugos, Dom, Dominguez-Salas, Duka, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Durazzo, Eldreth, Ernst, Ernst, Ernst, Ersche, Ersche, Fein, Fein, Fein, Fernandez-Serrano, Fernandez-Serrano, Franklin, Gansler, Gazdzinski, Gazdzinski, Gazdzinski, Gazdzinski, Giorgi, Glass, Goldstein, Goldstein, Hanlon, Hasin, Heinz, Hermann, Hirsiger, Hoefer, Holman, Humphreys, Hwang, Iudicello, Kalman, Ke, Kim, Klein, Koob, Le Berre, Licata, Loeber, Mackey, Matochik, Matochik, Medina, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Meyerhoff, Mon, Mon, Mon, Moorman, Morales, Moreno-Alcázar, Moss, Murray, Murray, Nader, Nicolas, Nordahl, Noyan, O'Neill, Oishi, Oscar-Berman, Oscar-Berman, Parks, Parvaz, Passetti, Pennington, Pennington, Pfefferbaum, Prescot, Prescot, Rabin, Rando, Rezapour, Rogers, Rourke, Rupp, Sailasuta, Salo, Schmidt, Schulte, Segobin, Seo, Seo, Simon, Sneider, Sorg, Stavro, Stevens, Streeter, Sullivan, Sullivan, Sullivan, Sullivan, Thompson, Tunving, van Eijk, Verdejo-Garcia, Verdejo-Garcia, Verdejo-Garcia, Volkow, Volkow, Volkow, Volkow, Volkow, Volkow, Volkow, Volkow, Vonmoos, Walitzer, Wang, Wang, Wang, Weber, Weinberger, Weinberger, Weinberger, Williams, Witkiewitz, Xiao, Yang, Yeh, Yoon, Younger, Yucel, Zahr, Zahr, Zatorre, Zou   +179 more
core   +1 more source