Results 81 to 90 of about 7,398,089 (304)
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Journal of Clinical Oncology, 2013 PURPOSE Chromosomal abnormalities, especially t(4;14) and del(17p), are major prognostic factors in patients with multiple myeloma (MM). However, this has been especially demonstrated in patients age < 66 years treated with intensive approaches. The goal
H. Avet-Loiseau +29 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
Flower-Like Plasma Cell Nuclei in Multiple Myeloma
Turkish Journal of Hematology, 2021 Abibatou Sall +6 more
doaj +1 more source
Experience of the diagnosis and observation of a child with wolf-hirschhorn syndrome
Zdorovʹe Rebenka, 2017 Modern data about the causes, course peculiarities, principles of diagnosis and symptomatic treatment of Wolf-Hirshhorn syndrome are given in the article. The description of own clinical case is presented.
L.V. Besh +5 more
doaj +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source
Blood, 2007 Acquired genomic aberrations have been shown to significantly impact survival in several hematologic malignancies. We analyzed the prognostic value of the most frequent chromosomal changes in a large series of patients with newly diagnosed symptomatic ...
H. Avet-Loiseau +33 more
semanticscholar +1 more source
Cytogenetic and FISH analysis of 93 multiple myeloma Moroccan patients
Molecular Genetics & Genomic Medicine, 2020 Background Multiple myeloma (MM) is a disease characterized by heterogeneous clinical presentations as well as complex genetic and molecular abnormalities.
Hasna Hamdaoui +9 more
doaj +1 more source
Abnormalities in Brain Esterases in Multiple Sclerosis.
Experimental Biology and Medicine, 1963 SummaryVertical starch-gel electrophoresis has been used for preparation of esterase zymograms of postmortem specimens of human brain. The specimens derived from 36 cases without a history of significant neurologic disability and 13 cases of multiple sclerosis.
Kevin D. Barron +2 more
openaire +3 more sources