Results 1 to 10 of about 620 (85)

Clinical Outcome and Risk Factors for Progression of Prenatally Diagnosed Fetal Ventriculomegaly: A Retrospective Multicenter Study. [PDF]

Prenat Diagn
ABSTRACT Objective To investigate the clinical outcome of fetuses with ventriculomegaly (VM), and to identify risk factors for progression of fetal VM in order to improve prenatal counseling. This was a multicenter, retrospective cohort study, comprising 229 cases with VM.
Moens A, Albersnagel Z, Veenhof MB, Adama van Scheltema PN, Sikkel E, Hoffer MJV, Faas BHW, Westra D, Feenstra I, Bijlsma EK, Santen GWE, Erasmus CE, Peeters-Scholte CMPCD.   +12 more
europepmc   +2 more sources

Pathology reporting of hepatoblastoma resections: recommendations from the international collaboration on cancer reporting. [PDF]

Histopathology
This is the first international dataset for the reporting of hepatoblastoma resection specimens produced by the International Collaboration on Cancer Reporting (ICCR). The aim is to standardize pathology reports, facilitating international data comparisons and improving management of hepatoblastoma on a global level.
López-Terrada DH, Webster F, Alaggio R, Bush JW, Cho SJ, de Krijger RR, Inoue T, O'Neill AF, Perez-Atayde AR, Ranganathan S, Stahlschmidt J, Tanaka Y, Cohen M, Reyes-Múgica M.   +13 more
europepmc   +2 more sources

Phenotype of patients with late diagnosis of 22q11 deletion: a review and retrospective study. [PDF]

Intern Med J
Abstract Background Chromosome 22q11.2 deletion syndrome (22q11DS) is the most common microdeletion syndrome, typically presenting in neonates with congenital cardiac anomalies, hypocalcaemia and thymic hypoplasia. Some patients are diagnosed later in adolescence and adulthood, with less known about the clinical phenotype of these patients.
Loh M, Schildkraut T, Byrnes A, Gelfand N, Gugasyan L, Horton AE, Hunter MF, Ojaimi S.   +7 more
europepmc   +2 more sources

Ribosomal Proteins in Cell Biology and Cancer

MedComm – Oncology, Volume 5, Issue 2, June 2026.
The functions of ribosomal proteins (RPs) extend beyond the conventional translation process, as they also regulate gene expression, stress responses, and disease progression. Dysregulation of RPs contributes to the onset and progression of various diseases, including cancer and ribosomopathies, underscoring their dual role as critical disease ...
Ao Zhang, Zeguang Sun, Xinyang Song, Xikun Zhou, Jing Li   +4 more
wiley   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

CAR‐T Cells: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 5, May 2026.
This graphical abstract outlines the current status, challenges, and future prospects of CAR‐T cells. The biological basis of CAR‐T cell therapy is the elegant redirection of adaptive immunity. Its initial successes have exposed a landscape of multifaceted challenges.
Aya Sedky Adly, Guillaume Cartron, Afnan Sedky Adly, Jean‐Christophe Egea, Pierre‐Yves Collart Dutilleul, Mahmoud Sedky Adly, Martin Villalba   +6 more
wiley   +1 more source

Narrative Ability in Swedish Children Treated for Posterior Fossa Tumours: Macro‐ and Microstructural Performance Before and 1–4 Weeks After Surgery

International Journal of Language &Communication Disorders, Volume 61, Issue 3, May/June 2026.
ABSTRACT Background Posterior fossa tumours (PFT), among the most common childhood brain tumours, place children at risk of speech, language, and communication difficulties, often described in relation to cerebellar mutism syndrome (CMS) but also seen in children without mutism.
K. Persson, D. Boeg Thomsen, K. Andersson, I. Tiberg, C. Castor, J. Grønbæk, R. Mathiasen, Å. Fyrberg   +7 more
wiley   +1 more source

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

Malignant Rhabdoid Tumors of the Liver Are Associated With Inferior Outcomes Compared to Other Extracranial Rhabdoid Tumors

Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Background Extracranial malignant rhabdoid tumors (eMRT) are rare, highly aggressive pediatric neoplasms. While the liver is a relatively common anatomic site of presentation, the clinical course of patients with hepatic eMRT (eMRT‐L) is not well described.
Sebastian Bühner, Katharina Gastberger, Stefanie Tüchert‐Knoll, Victoria E. Fincke, Pascal D. Johann, Patrick Melchior, Margarita Teleshova, Denis Kachanov, Alexey Shcherbakov, Irene Schmid, Kleoniki Roka, Reiner Siebert, Christian Vokuhl, Joachim Gerss, Jörg Fuchs, Rhoikos Furtwängler, Michael C. Frühwald   +16 more
wiley   +1 more source

Multimodal management and outcome of pediatric and adolescent malignant central nervous system tumors: A single‐center retrospective study

Malignancy Spectrum, Volume 2, Issue 3, Page 128-139, September 2025.
Abstract Objective There is a paucity of real‐world evidence in the Indian context to address the outcome of primary brain tumors (PBTs) in children. This study aimed to describe the demographic profile, clinical characteristics, and histological features of PBTs based on the 2016 World Health Organization classification, assess the efficacy of ...
Priyadharshini Veeralakshmanan, Wesley M. Jose, Suhas Udayakumaran, M. R. Bindhu, Debnarayan Dutta, Kannan Rajesh, Sruthi Kavalagunta, Renjitha Bhaskaran, Nikhil K. Haridas, M. P. Rakesh, Keechilat Pavithran   +10 more
wiley   +1 more source