Radiation-Induced Large Vessel Cerebral Vasculopathy in Pediatric Patients with Brain Tumors Treated with Proton Radiotherapy [PDF]
, 2017 Purpose The purpose of this research is to evaluate the incidence, time to development, imaging patterns, risk factors, and clinical significance of large vessel cerebral vasculopathy in pediatric patients with brain tumors treated with proton ...
Buchsbaum, Jeffrey +5 more
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New clinical developments in histone deacetylase inhibitors for epigenetic therapy of cancer [PDF]
, 2009 DNA methylation and histone acetylation are two well known epigenetic chromatin modifications. Epigenetic agents leading to DNA hypomethylation and histone hyperacetylation have been approved for treatment of hematological disorders.
Shundong Cang, Yuehua Ma, Delong Liu
core +1 more source
Presenting symptoms and time to diagnosis for Pediatric Central Nervous System Tumors in Qatar:a report from Pediatric Neuro-Oncology Service in Qatar [PDF]
, 2020 Introduction: There are no previous published reports on primary pediatric tumors of the central nervous system (CNS) in Qatar. We undertook this retrospective cohort study to review the diagnosis of CNS tumors in children in Qatar to analyze the ...
Al-Kharazi, Khalid +7 more
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Spectrum of developmental anomalies of the central nervous system encountered in a tertiary care hospital [PDF]
, 2018 Background: Congenital Central Nervous System (CNS) anomalies have typical and characteristic imaging features. Imaging plays a pivotal role in their diagnosis.
Bhagat, Savitri +3 more
core +2 more sources
Inhibition of the NLRP3 inflammasome using MCC950 reduces vincristine-induced adverse effects in an acute lymphoblastic leukemia patient-derived xenograft model. [PDF]
HemasphereAbstract Vincristine is one of the most important chemotherapeutic drugs used to treat acute lymphoblastic leukemia (ALL). Unfortunately, vincristine often causes severe adverse effects, including sensory–motor neuropathies, weight loss, and overall decreased well‐being, that are difficult to control and that decrease the quality of life and survival ...
Starobova H +8 more
europepmc +2 more sources
Improved prediction of postoperative paediatric cerebellar mutism syndrome using an artificial neural network [PDF]
, 2022 BACKGROUND: Postoperative paediatric cerebellar mutism syndrome (pCMS) is a common but severe complication which may arise following the resection of posterior fossa tumours in children.
Aquilina, K +10 more
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Epidemiological investigation and ultrasonographic results of developmental dysplasia of the hip in infants aged 0-6 months [PDF]
, 2023 Aim: To determine the prevalence of developmental dysplasia of the hip (DDH), a common condition in our region, and investigate the underlying factors contributing to its occurrence.
Akar, Mehmet Sait, Ulus, Sait Anil
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Atypical teratoid/ rhabdoid tumour in adult - A rare case report [PDF]
, 2014 Atypical teratoid rhabdoid tumour is a rare and very aggressive malignant embryonal tumour of central nervous system (CNS) seen in infancy and early childhood.
Manas +3 more
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Applications of Frameless Image-Guided Robotic Stereotactic Radiotherapy and Radiosurgery in Pediatric Neuro-Oncology: A Systematic Review [PDF]
, 2022 Background: CyberKnife-based robotic radiosurgery (RRS) is a widely used treatment modality for various benign and malignant tumors of the central nervous system (CNS) in adults due to its high precision, favorable safety profile, and efficacy.
Budach, Volker +3 more
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Cerebral organoid research for pediatric patients with neurological disorders. [PDF]
Clin Exp PediatrCerebral organoids derived from human induced pluripotent stem cells offer a groundbreaking foundation for the analysis of pediatric neurological diseases. Unlike organoids from other somatic systems, cerebral organoids present unique challenges, such as
Eun J, Lee JE, Yang SH.
europepmc +3 more sources