Results 51 to 60 of about 1,204,086 (248)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Diastasis recti in children – results of ultrasonographic study

open access: yesJournal of Ultrasonography
Diastasis recti is a common contour abnormality of the anterior abdominal wall, where an increased distance between the rectus abdominis muscles results in a visible or palpable bulge in this area. This study aimed to characterize this clinical entity in
Kawalec-Rutkowska Agata Maria   +1 more
doaj   +1 more source

Association of Immunoglobulin G Abnormalities in Diseases: A Mini Review

open access: yesLife Sciences, Medicine and Biomedicine, 2018
Immunoglobulins are antibodies that play important roles in preserving our immune system. They have the ability to initiate humoral responses and remove antigen from the body.
Audrey Siew Foong Kow   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Abnormal left single pulmonary vein: case report of an anecdotal variant

open access: yesJournal of the Belgian Society of Radiology, 2011
We describe here a patient with a very rare ectopic unilateral single pulmonary vein, with normal distal drainage into the left atrium, and thus a non pathologic finding to be distinguished from clinically significant abnormalities.
M Bersou, P Mailleux
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Frequency of Uterine Malformation among Women in a Restricted Gene Pool Community : A retrospective cross-sectional study in La Crete, Canada

open access: yesSultan Qaboos University Medical Journal, 2007
Objective: This random retrospective cross-sectional study was done to determine the incidence of uterine malformation in 4 groups of women desiring to conceive during their reproductive years, all of them living in La Crete, a community in Northern ...
Saad Ramzi Ismail
doaj  

Slipped capital femoral epiphysis

open access: yesJournal of the Belgian Society of Radiology, 2014
Background: A 10-year-old boy presented with a 4-week history of limping gait and right knee pain. The patient did not have a fever. Physical examination revealed limited range of motion of the right hip.
L Topff, G Gelin, M Grieten
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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