Results 71 to 80 of about 2,286,481 (339)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Persistent stapedial artery: a congenital anomaly to know
Journal of the Belgian Society of Radiology, 2013 Persistent stapedial artery, one of the rare arterial congenital anomalies of the middle ear, is important to know due to its possible clinical repercussions.
MI Nica, G Cosnard
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Morphological abnormalities in Tribolium castaneum (Herbst) and Tribolium confusum Duval due to cyromazine and pirimiphos-methyl treatments alone or in combination [PDF]
Invertebrate Survival Journal, 2006 Newly hatched (24 h old) larvae of Tribolium castaneum and T. confusum were allowed to feed on different doses of cyromazine or pirimiphos-methyl, or on a combined dose of both compounds up to pupation.
AHM Kamaruzzaman +3 more
doaj
Brain MRI Findings of the Cri-Du-Chat Syndrome: A Case Report and Summary
대한영상의학회지, 2020 Cri-du-chat syndrome is a rare genetic disorder in which the patient presents with a characteristic high-pitched monotonous cry and recurrent aspiration pneumonia, attributed to abnormalities in the larynx, epiglottis, and nervous system.
Jin Sol Choi +3 more
doaj +1 more source
Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2. [PDF]
, 2014 Lamins B1 and B2 (B-type lamins) have very similar sequences and are expressed ubiquitously. In addition, both Lmnb1- and Lmnb2-deficient mice die soon after birth with neuronal layering abnormalities in the cerebral cortex, a consequence of defective ...
Coffinier, Catherine +10 more
core
Motor deficits in schizophrenia quantified by nonlinear analysis of postural sway. [PDF]
, 2012 Motor dysfunction is a consistently reported but understudied aspect of schizophrenia. Postural sway area was examined in individuals with schizophrenia under four conditions with different amounts of visual and proprioceptive feedback: eyes open or ...
Bolbecker, Amanda R. +6 more
core +3 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Association of Immunoglobulin G Abnormalities in Diseases: A Mini Review
Life Sciences, Medicine and Biomedicine, 2018 Immunoglobulins are antibodies that play important roles in preserving our immune system. They have the ability to initiate humoral responses and remove antigen from the body.
Audrey Siew Foong Kow +2 more
doaj +1 more source