Results 51 to 60 of about 104,079 (307)

Risk Factors for Spontaneous Abortion [PDF]

, 2017
A case-control study was conducted to evaluate risk factors for spontaneous abortions. Cases were 94 women with two or more unexplained miscarriages (after exclusion of genetic, endocrine and Müllerian factors) and no term pregnancy, controls were 176 ...
ACAIA, BARBARA, BOCCIOLONE, LUCA, FEDELE, LUIGI, LA VECCHIA, CARLO, NEGRI, EVA, PARAZZINI, FABIO   +5 more
core  

Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]

, 2011
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
El Hajj, N., Gromoll, J., Haaf, T., Hahn, T., Schneider, E., Schorsch, M., Tresch, A., Zechner, Ulrich   +7 more
core   +1 more source

Variant Update on ASCC1: Characterization of the First Homozygous Missense Variant Involved in Prenatal‐Onset Spinal Muscular Atrophy With Congenital Bone Fractures 2

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Spinal muscular atrophy with congenital bone fractures 2 is a rare and severe autosomal recessive neuromuscular disorder caused by pathogenic variants in ASCC1. This condition characterized by prenatal onset of severe hypotonia with fetal hypokinesia and congenital contractures results in arthrogryposis multiplex congenita, and increased ...
A. Civit, L. Kerbellec, D. Laurenceau, D. C. Ung, M. P. Moizard, N. Ronce, P. Gueguen, F. Laumonnier, A. C. Bréhin, F. Marguet, A. Laquerrière, A. M. Bergemer Fouquet, J. Cirier, S. Blesson, S. Arpin, M. Jeanne, M. L. Vuillaume   +16 more
wiley   +1 more source

Relationship between consanguineous marriage and spontaneous abortion and stillbirth

Payesh, 2018
Objective (s): spontaneous abortion and stillbirth has always been a devastating experience for the mother and of concern in clinical practice. Since consanguineous marriage is common in Iran, high rates of congenital malformations and genetic diseases ...
Mehri Shams Ghahfarokhi
doaj  

Increased Circulating Levels of Tissue-Type Plasminogen Activator Are Associated with the Risk of Spontaneous Abortion During the First Trimester of Pregnancy

Diagnostics, 2020
Spontaneous abortion is a common complication in early pregnancy, with an incidence of around 20%. Ultrasound scan and measurement of human chorionic gonadotropin are used to identify patients at risk of spontaneous abortion; however, there is a clinical
Lara J. Monteiro, Manuel Varas-Godoy, Stephanie Acuña-Gallardo, Paula Correa, Gianluca Passalacqua, Max Monckeberg, Gregory E. Rice, Sebastián E. Illanes   +7 more
doaj   +1 more source

How long is expectant management safe in first-trimester miscarriage? [PDF]

, 2005
More than 80% of women with a first-trimester spontaneous abortion have complete natural passage of tissue within 2 to 6 weeks with no higher complication rate than that from surgical intervention (strength of recommendation [SOR]: A, based on multiple ...
Butler, Charles, Kelsberg, Gary, St. Anna, Leilani   +2 more
core  

Caffeine intake during pregnancy and adverse birth outcomes: a systematic review and dose–response meta-analysis [PDF]

, 2014
Caffeine is commonly consumed during pregnancy, crosses the placenta, with fetal serum concentrations similar to the mother’s, but studies of birth outcome show conflicting findings. We systematically searched Medline and Embase for relevant publications.
Cade, JE, Garrard, L, Greenwood, DC, Keogh, G, King, LG, Thatcher, NJ, Ye, J   +6 more
core   +1 more source

Variants in AKR1D1 and Infant Mortality: Should Bile Acid Screening be a Routine Part of Newborn Screening?

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic pathogenic variants in AKR1D1 cause Δ4‐3‐oxosteroid 5β‐reductase deficiency, disrupt bile acid synthesis, and result in Congenital Bile Acid Synthesis defect type 2 (CBAS2). CBAS2 presents in infancy with cholestasis, coagulopathy, and failure to thrive.
Jade Hudson, Stephanie Hyunh, Bojana Rakic, Cornelius Boerkoel   +3 more
wiley   +1 more source

DDN gene downregulation in endometrium: a potential immune-mediated link between bipolar disorder and spontaneous abortion revealed by Mendelian randomization and bioinformatics

Beni-Suef University Journal of Basic and Applied Sciences
Background Spontaneous abortion, affecting over 20% of pregnancies, presents significant physical and psychological burdens. While chromosomal aneuploidy and environmental factors contribute to its etiology, the role of maternal genetic and psychiatric ...
Jian Tang, Zhixin Xu, Lingling Yang, Qiong Zou   +3 more
doaj   +1 more source

Interleukin-18 gene promoter polymorphisms and recurrent spontaneous abortion [PDF]

Background: IL-18 is a multifunctional cytokine capable of inducing either Th1 or Th2 polarization depending on the immunologic milieu. IL-18 is detected at the materno-fetal interface very soon in early pregnancy.
امانی, داور, صمصامی دهقان, عالم تاج, فتوحی قیام, علی رضا, قادری, عباس, مجتهدی, زهرا, نعیمی, سیروس   +5 more
core   +1 more source