Results 41 to 50 of about 201,555 (341)

Effects of Different Toothpastes on the Nanomechanical Properties and Chemical Composition of Resin-Modified Glass Ionomer Cement and Composite Resin Restorations

open access: yesDentistry Journal, 2023
Purpose: This study evaluates the effects of different toothpastes on the nanohardness and chemical compositions of restorative materials and dental surfaces.
Mariana Dias Moda   +6 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Rocketdyne's advanced coal slurry pumping program [PDF]

open access: yes, 1977
The Rocketdyne Division of Rockwell International Corporation is conducting a program for the engineering, fabrication, and testing of an experimental/prototype high-capacity, high-pressure centrifugal slurry feed pump for coal liquefaction purposes. The
Davis, D. E., Gilman, H. H., Wong, G. S.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Effect of Carbon Content on Abrasive Impact Wear Behavior of Cr-Si-Mn Low Alloy Wear Resistant Cast Steels

open access: yesFrontiers in Materials, 2019
The effects of carbon contents on microstructure evolution and mechanical properties, including hardness, impact toughness and abrasive impact wear resistance behavior, were investigated for Cr-Si-Mn low alloy cast steels.
Xiaodong Wang   +5 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Metodologia para avaliação do desgaste em ferramentas simétricas de mobilização do solo Methodology for assessment of wear rate in symmetrical soil-engaging tools

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2009
A correta avaliação e previsão do tempo de vida útil dos mecanismos que atuam no rompimento do solo, são importantes na análise de equipamentos. O desgaste deste tipo de ferramenta (ponteiras sulcadoras de semeadoras, de escarificadores e de subsoladores)
Antônio L. T. Machado   +5 more
doaj   +1 more source

Abrasiveness and whitening effect of charcoal-containing whitening toothpastes in permanent teeth.

open access: yesDental Research Journal, 2021
Background: Charcoal toothpastes can whiten teeth through abrasion. The purpose of this study was to determine the level of whitening and abrasiveness of charcoal toothpastes in permanent teeth. Materials and Methods: In this in vitro study, 30 premolars
Masoud Fallahinejad Ghajari   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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