Results 51 to 60 of about 203,365 (341)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Some remarks on particle size effects on the abrasion of a range of Fe based alloys [PDF]

, 2010
The low-stress three body abrasion behaviour of a range of steels was investigated. The tests were carried out in a rubber wheel tester (according to ASTM G65-94, reapproved in 2000) at room temperature.
Almeraya-Calderon, F., Cabral-Miramontes, J.A., Chacon-Nava, J. G., Martinez-Villafañe, A., Stack, M.M.   +4 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Preparation and wear properties of high-silicon high-vanadium wear-resistant alloy with nano pearlite matrix and carbides composite structure

Journal of Materials Research and Technology
Combining high hardness carbide of high vanadium cast iron with nano pearlite, which has high strength and toughness, represents an innovative attempt to explore a new technology for preparing high vanadium alloy.
Hongshen Xie, Wanqing Leng, Ming Li, Litao Yin, Zhou Li, Chenhui Zhu, Xuke Yao, Liujie Xu   +7 more
doaj   +1 more source

Effect of Carbon Content on Abrasive Impact Wear Behavior of Cr-Si-Mn Low Alloy Wear Resistant Cast Steels

Frontiers in Materials, 2019
The effects of carbon contents on microstructure evolution and mechanical properties, including hardness, impact toughness and abrasive impact wear resistance behavior, were investigated for Cr-Si-Mn low alloy cast steels.
Xiaodong Wang, Xiaodong Wang, Yunbo Chen, Shizhong Wei, Lingli Zuo, Feng Mao   +5 more
doaj   +1 more source

Extruded and injection moulded virgin PA 6/6 as abrasion resistant material [PDF]

, 2017
Polyamide (PA6/6) is often used as a tribological pair in abrasion prevalent applications such as hinges and sliders. PA6/6 is frequently processed by injection moulding and extrusion process.
Biswas, Sandhyaranieditor, De Baets, PatrickTW08TW51TW568010007297790000-0002-0552-3850F46EAEFE-F0ED-11E1-A9DE-61C894A0A6B4, Hayder, Al-maliki, Kalacska, Gabor, Keresztes, Roberts, Neis, Patric D, Sukumaran, JacobUGent00009146028680200080644997192789318427B27214-F0EE-11E1-A9DE-61C894A0A6B4   +6 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Abrasiveness and whitening effect of charcoal-containing whitening toothpastes in permanent teeth.

Dental Research Journal, 2021
Background: Charcoal toothpastes can whiten teeth through abrasion. The purpose of this study was to determine the level of whitening and abrasiveness of charcoal toothpastes in permanent teeth. Materials and Methods: In this in vitro study, 30 premolars
Masoud Fallahinejad Ghajari, Maryam Shamsaei, Kimia Basandeh, Maedeh Sadeghpour Galouyak   +3 more
doaj   +1 more source

Rocketdyne's advanced coal slurry pumping program [PDF]

, 1977
The Rocketdyne Division of Rockwell International Corporation is conducting a program for the engineering, fabrication, and testing of an experimental/prototype high-capacity, high-pressure centrifugal slurry feed pump for coal liquefaction purposes. The
Davis, D. E., Gilman, H. H., Wong, G. S.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source