Results 41 to 50 of about 104,408 (238)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Jin'gangshi yu moliao moju gongchengObjectivesDue to the complexity of the grinding process, the study of the grinding mechanism has always been a research hotspot in the field of precision grinding.
Xiaodong CHEN +4 more
doaj +1 more source
, 1971 Resilient wheel design with woven wire tire and abrasive treads for lunar surface ...
Calandro, J. N. +2 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Experimental Research Work to Optimize Process Parameters into Electro Chemical Abrasive Flow Machining using Taguchi Methodology [PDF]
, 2017 Electrochemical assisted abrasive flow finishing is a newly developed hybrid finishing process which is used to finish the internal parts of work piece having complicated geometry to large extent.
Kumar, Sunil, Singh, Sandeep
core
The influence of surface treatment of PVD coating on its quality and wear resistant [PDF]
, 2019 The article deals with a determination of the influence of a cutting edge preparation on the quality and wear resistance of coated cutting tools. Cutting inserts made from a sintered carbide with a deposited layer of PVD coating were selected for ...
Malotová, Šárka +3 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Cracks in glass electrical connector headers removed by dry blasting with fine abrasive [PDF]
, 1967 Cracking that causes pressure leakage in glass connector headers can be alleviated by manipulating the pin bridgewire connectors. This initiates the surface and meniscus cracks.
Eckert, R. W.
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Applied Sciences, 2022 This paper proposes a gel-formed abrasive tool to address the problem of abrasive agglomeration in a traditional hot-pressing abrasive tool. The effect of Polyimide resin content on the mechanical properties of the gel abrasive tools were tested, and a ...
Liang Zhao +4 more
doaj +1 more source