Results 61 to 70 of about 5,427 (131)

A Case Report Demonstrating the Potential Clinical Benefit of Exhaustive Molecular Profiling in an Aggressive Muscle-Invasive High-Grade Metastatic Urothelial Carcinoma

open access: yesCase Reports in Oncology, 2017
We present a muscle-invasive high-grade metastatic urothelial carcinoma patient, aged 71 years, with rapid progression from the diagnosis and a poor prognosis after 3 lines of treatment.
Amaya Ramírez de Olano   +6 more
doaj   +1 more source

Safety and Efficacy of -Paclitaxel in the Treatment of Patients with Breast Cancer

open access: yesBreast Cancer: Basic and Clinical Research, 2011
Taxanes are highly active chemotherapeutic agents in the treatment of early-stage and metastatic breast cancer. Novel formulations have been developed to improve efficacy and decrease toxicity associated with these cytotoxic agents.
Prakash Vishnu, Vivek Roy
doaj   +1 more source

Nanoparticle abraxane possesses impaired proliferation in A549 cells due to the underexpression of glucosamine 6-phosphate N-acetyltransferase 1 (GNPNAT1/GNA1)

open access: yesInternational Journal of Nanomedicine, 2017
Minzhi Zhao,* Haiyun Li,* Yan Ma, He Gong, Shu Yang, Qiaojun Fang, Zhiyuan Hu Chinese Academy of Sciences Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience ...
Zhao MZ   +6 more
doaj  

First line treatment of advanced non-small-cell lung cancer – specific focus on albumin bound paclitaxel

open access: yesInternational Journal of Nanomedicine, 2013
Neha Gupta, Hassan Hatoum, Grace K DyDepartment of Medicine, Roswell Park Cancer Institute, Buffalo, NY, USAAbstract: Lung cancer is the leading cause of cancer mortality worldwide in both men and women.
Gupta N, Hatoum H, Dy GK
doaj  

GNQ-209P Mutation in Metastatic Uveal Melanoma and Treatment Outcome

open access: yesCase Reports in Oncological Medicine, 2018
Metastatic prognosis in uveal melanoma is assessed by gene expression profiling (GEP) testing of the tumor cells, usually obtained by fine needle aspiration (FNA).
Nagla Abdel Karim   +6 more
doaj   +1 more source

Nab-paclitaxel, docetaxel, or solvent-based paclitaxel in metastatic breast cancer: a cost-utility analysis from a Chinese health care perspective

open access: yesClinicoEconomics and Outcomes Research, 2015
George Dranitsaris,1 Bo Yu,2 Jennifer King,3 Satyin Kaura,3 Adams Zhang3 1Augmentium Pharma Consulting Inc., Toronto, ON, Canada; 2Fudan University Shanghai Cancer Center, Shanghai, People's Republic of China; 3Celgene Corporation, Summit, NJ, USA ...
Dranitsaris G   +4 more
doaj  

Human Serum Albumin Grafted by Monomeric and Polymeric β-Cyclodextrin as Drug Delivery System for Levofloxacin with Improved Pharmacological Properties

open access: yesFuture Pharmacology
Human serum albumin (HSA) is a multifunctional protein, known to be a natural carrier for a number of endogenous and exogenous compounds, including drugs.
Tatiana Yu Kopnova   +3 more
doaj   +1 more source

Iodine-125 brachytherapy triggers immunogenic cell death and potentiates anti-PD-L1 immunotherapy in bone metastatic triple-negative breast cancer

open access: yesFrontiers in Immunology
IntroductionTriple-negative breast cancer (TNBC) with bone metastasis is challenging to treat due to an immunosuppressive microenvironment and the limited, transient immune activation from conventional external beam radiotherapy.
Min Li   +12 more
doaj   +1 more source

Non-genetically reprogrammed meta-neutrophils potentiate chemo-immunotherapy against lung metastatic triple-negative breast cancer. [PDF]

open access: yesCell Rep Med
Hao M   +13 more
europepmc   +1 more source

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