Results 111 to 120 of about 2,037,182 (380)

Differentiating Interictal and Ictal States in Childhood Absence Epilepsy through Permutation Rényi Entropy

open access: yesEntropy, 2015
Permutation entropy (PE) has been widely exploited to measure the complexity of the electroencephalogram (EEG), especially when complexity is linked to diagnostic information embedded in the EEG. Recently, the authors proposed a spatial-temporal analysis
N. Mammone   +3 more
semanticscholar   +1 more source

Safety profile of oxcarbazepine: results from a prescription-event monitoring study [PDF]

open access: yes, 2010
Purpose: To monitor safety of oxcarbazepine, prescribed in primary care in England, using prescription-event monitoring (PEM). Methods: Postmarketing surveillance using observational cohort technique of PEM.
Buggy, Y.   +3 more
core   +1 more source

Targeting Multilayered Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery Strategies

open access: yesAdvanced Science, EarlyView.
Brain diseases involve multilayered metabolic disruptions that reshape cellular interactions and microenvironments. This review outlines core metabolic features across disease states and presents emerging nanodelivery strategies as precision tools to reprogram pathological metabolism.
Jingyi Zhou, Chen Jiang
wiley   +1 more source

Detection and Prediction of Absence Seizures Based on Nonlinear Analysis of the EEG in Wag/Rij Animal Model

open access: yesInternational Clinical Neuroscience Journal, 2018
Background: Epilepsy is a common neurological disorder with a prevalence of 1% of the world population. Absence epilepsy is a form of generalized seizures with Spike wave discharge in EEG.
Saleh Lashkari   +4 more
doaj   +1 more source

CaV3.2 calcium channels control NMDA receptor-mediated transmission: a new mechanism for absence epilepsy

open access: yesGenes & Development, 2015
Wang et al. show that CaV3.2 channels control NMDA-sensitive glutamatergic receptor (R)-mediated transmission and subsequent NMDA-R-dependent plasticity of AMPA-R-mediated transmission at rat central synapses.
Guangfu Wang   +15 more
semanticscholar   +1 more source

On the role of the corpus callosum in interhemispheric functional connectivity in humans [PDF]

open access: yes, 2017
Resting state functional connectivity is defined in terms of temporal correlations between physiologic signals, most commonly studied using functional magnetic resonance imaging. Major features of functional connectivity correspond to structural (axonal)
Hacker, Carl D.   +8 more
core   +2 more sources

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

Functional Network Connectivity Patterns between Idiopathic Generalized Epilepsy with Myoclonic and Absence Seizures

open access: yesFrontiers in Computational Neuroscience, 2017
The extensive cerebral cortex and subcortical structures are considered as the major regions related to the generalized epileptiform discharges in idiopathic generalized epilepsy.
Qifu Li   +7 more
doaj   +1 more source

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

open access: yesAdvanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen   +16 more
wiley   +1 more source

Complexity of Multi-Channel Electroencephalogram Signal Analysis in Childhood Absence Epilepsy

open access: yesPLoS ONE, 2015
Absence epilepsy is an important epileptic syndrome in children. Multiscale entropy (MSE), an entropy-based method to measure dynamic complexity at multiple temporal scales, is helpful to disclose the information of brain connectivity.
W. Weng   +6 more
semanticscholar   +1 more source

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