Results 121 to 130 of about 2,304,558 (334)
Long-Term Follow-Up of Juvenile Myoclonic Epilepsy
Pediatric Neurology Briefs, 2006 A population of 257 juvenile myoclonic epilepsy (JME) patients and family members was prospectively evaluated in a study at UCLA School of Medicine and international centers.
J Gordon Millichap
doaj +1 more source
[A case of epilepsy with myoclonoic absences].
No to hattatsu = Brain and development, 1989 A case of epilepsy with myoclonic absences is reported. A boy, 3 years and 8 months old, had the first attack at the age of 1 year and 8 months. He was mentally retarded, but had no evidence of organic brain damages. He had been said to have "absence" at another hospital for 2 years until he was referred to our hospital.
Kameda, Keiji +5 more
openaire +2 more sources
Genes & Development, 2015 Wang et al. show that CaV3.2 channels control NMDA-sensitive glutamatergic receptor (R)-mediated transmission and subsequent NMDA-R-dependent plasticity of AMPA-R-mediated transmission at rat central synapses.
Guangfu Wang +15 more
semanticscholar +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
, 2011 Childhood absence epilepsy (CAE) and benign childhood epilepsy with centrotemporal spikes (BCECTS), or benign rolandic epilepsy (BRE), are the most common forms of childhood epilepsy.
Curatolo, Paolo +13 more
core +1 more source
Gender issues in antiepileptogenic treatments
Neurobiology of Disease, 2014 Disease modification of epilepsy refers to the alleviation of epileptogenesis or comorbidities after genetic or acquired epileptogenic brain insults. There are currently 30 proof-of-concept experimental pharmacologic studies that have demonstrated some ...
Asla Pitkänen +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Lacosamide Increases Absence Seizures and Anxiety-Like Behavior in WAG/Rij Rat Model
, 2022 Objective:The aim of the present study was to evaluate the effects of antiepileptic drug lacosamide on spontaneous absence seizures and anxiety in genetic absence-epilepsy WAG/Rij rats.Methods:Tripolar electrodes were placed in the cortex of WAG/Rij rats
Orhan Sümbül +2 more
core +1 more source
Frontiers in Computational Neuroscience, 2017 The extensive cerebral cortex and subcortical structures are considered as the major regions related to the generalized epileptiform discharges in idiopathic generalized epilepsy.
Qifu Li +7 more
doaj +1 more source
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source