Results 11 to 20 of about 128,227 (258)
HCN channels and absence seizures [PDF]
Hyperpolarization-activation cyclic nucleotide-gated (HCN) channels were for the first time implicated in absence seizures (ASs) when an abnormal Ih (the current generated by these channels) was reported in neocortical layer 5 neurons of a mouse model. Genetic studies of large cohorts of children with Childhood Absence Epilepsy (where ASs are the only ...
Crunelli Vincenzo +3 more
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Up to 20% of pediatric patients with primary generalized epilepsy (PGE) will not respond effectively to medication for seizure control. Responsive neurostimulation (RNS) is a promising therapy for pediatric patients with drug-resistant epilepsy and has ...
William P. Welch +3 more
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Electroencephalography in the Diagnosis of Genetic Generalized Epilepsy Syndromes
Genetic generalized epilepsy (GGE) consists of several syndromes diagnosed and classified on the basis of clinical features and electroencephalographic (EEG) abnormalities. The main EEG feature of GGE is bilateral, synchronous, symmetric, and generalized
Udaya Seneviratne +3 more
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Tonic–Absence Seizures: An Underrecognized Seizure Type [PDF]
Summary: Purpose: The individual electroclinical patterns—tonic seizures with generalized paroxysmal fast activity (GPFA, activity >13 Hz), and absence seizures with generalized slow spike‐and‐wave activity (GSS&W, <3 Hz)—have been extensively described in the literature.
Tina T, Shih, Lawrence J, Hirsch
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Multimodal detection of typical absence seizures in home environment with wearable electrodes
Patients with absence epilepsy fail to report almost 90% of their seizures. The clinical gold standard to assess absence seizures is video-electroencephalography (vEEG) recorded in the hospital, an expensive and obtrusive procedure which requires also ...
Christos Chatzichristos +6 more
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Perampanel and childhood absence epilepsy: A real life experience
ObjectivesThe aim of our study was to evaluate the effectiveness and tolerability of perampanel (PER) as first add-on and as second line monotherapy in subjects with childhood absence epilepsy.MethodsOur sample consisted of 20 patients with childhood ...
Francesca Felicia Operto +14 more
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The Presence of Consciousness in Absence Seizures [PDF]
This paper examines three respects in which the study of epileptic absence seizures promises to inform our understanding of consciousness. Firstly, it has the potential to bear on debates concerning the behavioural and cognitive functions associated with consciousness.
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Adrenergic mechanisms of absence status epilepticus
Absence status epilepticus is a prolonged, generalized absence seizure that lasts more than half an hour. The mechanisms underlying the absence of status epilepticus are still not entirely understood.
Evgenia Sitnikova
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Objective: Our aim was to investigate the dynamics of functional connectivity (FC) networks during seizure termination in patients with childhood absence epilepsy (CAE) using magnetoencephalography (MEG) and graph theory (GT) analysis.Methods: MEG data ...
Jintao Sun +7 more
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Absence seizure associated with coloprep consumption in colonoscopy
Coloprep is a bowel preparatory solution given before endoscopic procedures to get a unobscured internal vision. It has among its constituents’ sodium sulphate, potassium sulphate and magnesium sulphate which produce an osmotic effect in the bowel ...
Abin Chandrakumar +4 more
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