Results 21 to 30 of about 2,358,919 (290)
Respiratory alkalosis provokes spike-wave discharges in seizure-prone rats
eLife, 2022 Hyperventilation reliably provokes seizures in patients diagnosed with absence epilepsy. Despite this predictable patient response, the mechanisms that enable hyperventilation to powerfully activate absence seizure-generating circuits remain entirely ...
Kathryn A Salvati +6 more
doaj +1 more source
HCN channels and absence seizures [PDF]
Neurobiology of Disease, 2023 Hyperpolarization-activation cyclic nucleotide-gated (HCN) channels were for the first time implicated in absence seizures (ASs) when an abnormal Ih (the current generated by these channels) was reported in neocortical layer 5 neurons of a mouse model. Genetic studies of large cohorts of children with Childhood Absence Epilepsy (where ASs are the only ...
Crunelli Vincenzo +3 more
openaire +4 more sources
International Journal of Neural Systems, 2020 Advances in electroencephalography (EEG) equipment now allow monitoring of people with epilepsy in their daily-life environment. The large volumes of data that can be collected from long-term out-of-clinic monitoring require novel algorithms to process ...
J. Dan +4 more
semanticscholar +1 more source
Seizure, 2020 PURPOSE When performed correctly, hyperventilation (HV) for three minutes provokes absence seizures in virtually all children, a finding suggestive of a diagnosis of childhood absence epilepsy (CAE).
Tal Rozenblat +4 more
semanticscholar +1 more source
Frontiers in Neurology, 2021 Up to 20% of pediatric patients with primary generalized epilepsy (PGE) will not respond effectively to medication for seizure control. Responsive neurostimulation (RNS) is a promising therapy for pediatric patients with drug-resistant epilepsy and has ...
William P. Welch +3 more
doaj +1 more source
Multimodal detection of typical absence seizures in home environment with wearable electrodes
Frontiers in Signal Processing, 2022 Patients with absence epilepsy fail to report almost 90% of their seizures. The clinical gold standard to assess absence seizures is video-electroencephalography (vEEG) recorded in the hospital, an expensive and obtrusive procedure which requires also ...
Christos Chatzichristos +6 more
doaj +1 more source
Perampanel and childhood absence epilepsy: A real life experience
Frontiers in Neurology, 2022 ObjectivesThe aim of our study was to evaluate the effectiveness and tolerability of perampanel (PER) as first add-on and as second line monotherapy in subjects with childhood absence epilepsy.MethodsOur sample consisted of 20 patients with childhood ...
Francesca Felicia Operto +14 more
doaj +1 more source
Electroencephalography in the Diagnosis of Genetic Generalized Epilepsy Syndromes
Frontiers in Neurology, 2017 Genetic generalized epilepsy (GGE) consists of several syndromes diagnosed and classified on the basis of clinical features and electroencephalographic (EEG) abnormalities. The main EEG feature of GGE is bilateral, synchronous, symmetric, and generalized
Udaya Seneviratne +3 more
doaj +1 more source
Tonic–Absence Seizures: An Underrecognized Seizure Type [PDF]
Epilepsia, 2003 Summary: Purpose: The individual electroclinical patterns—tonic seizures with generalized paroxysmal fast activity (GPFA, activity >13 Hz), and absence seizures with generalized slow spike‐and‐wave activity (GSS&W, <3 Hz)—have been extensively described in the literature.
Tina T, Shih, Lawrence J, Hirsch
openaire +2 more sources