Results 71 to 80 of about 75,216 (280)
Stability of matrix factorization for collaborative filtering [PDF]
, 2012 We study the stability vis a vis adversarial noise of matrix factorization algorithm for matrix completion. In particular, our results include: (I) we bound the gap between the solution matrix of the factorization method and the ground truth in terms of ...
Wang, Yu-Xiang, Xu, Huan
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Relative directed homotopy theory of partially ordered spaces [PDF]
, 2006 Algebraic topological methods have been used successfully in concurrency theory, the domain of theoretical computer science that deals with distributed computing. L. Fajstrup, E. Goubault, and M. Raussen have introduced partially ordered spaces (pospaces)
Kahl, Thomas
core +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Cell Transplantation, 2021 Stomach adenocarcinoma (STAD) is a highly heterogeneous disease. Due to the lack of effective molecular markers and personalized treatment, the prognosis of gastric cancer patients is still very poor.
Chenxia Ren +4 more
doaj +1 more source
A computer algebra user interface manifesto [PDF]
, 2013 Many computer algebra systems have more than 1000 built-in functions, making expertise difficult. Using mock dialog boxes, this article describes a proposed interactive general-purpose wizard for organizing optional transformations and allowing easy fine
Stoutemyer, David R.
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A new joint CTC-attention-based speech recognition model with multi-level multi-head attention
EURASIP Journal on Audio, Speech, and Music Processing, 2019 A method called joint connectionist temporal classification (CTC)-attention-based speech recognition has recently received increasing focus and has achieved impressive performance.
Chu-Xiong Qin, Wen-Lin Zhang, Dan Qu
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source