Results 171 to 180 of about 1,308,562 (279)

Identification of an optimal absolute lymphocyte count at leukapheresis in patients with lymphoma treated with CART. [PDF]

Blood Immunol Cell Ther
Kim K, Hunzeker Z, Sun X, Sun R, Voorhees T, Youssef Y, Epperla N, De Castro M, Ow K, Santiago M, Varghese J, Ayers A, Ramdial J, Hosing C, Kebriaei P, Shpall E, Jain M, Chavez J, Locke FL, Neelapu SS, Ahmed S, Strati P.   +21 more
europepmc   +1 more source

Isolating T‐Cell Potent Lentiviral Vector Subpopulations through Rational Design of Nanofiber Anion‐Exchange Adsorbents

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter, Gyorgy Ovari, Anurag Kulkarni, Thomas Williams‐Fegredo, Carol Knevelman, Kyriacos Mitrophanous, Lee Davies, Farzad Foroutan, Matthew Townsend, Stephen Goldrick, Daniel G. Bracewell   +10 more
wiley   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Antithymocyte Globulin Induction Dosed on Ideal Body Weight: Absolute Lymphocyte Count (ALC) Depletion in Kidney Transplant Recipients with and without Obesity. [PDF]

Clin Transplant
Ramos R, Benken ST, Benken JJ.
europepmc   +1 more source

Red Cell Distribution Width and Absolute Lymphocyte Count Associate With Biomarkers of Inflammation and Subsequent Mortality in Rheumatoid Arthritis. [PDF]

J Rheumatol, 2023
Lange A, Kostadinova L, Damjanovska S, Gad I, Syed S, Siddiqui H, Yousif P, Kowal CM, Shive C, Burant C, Singer N, Bej T, Al-Kindi S, Wilson B, Mattar M, Zidar DA, Anthony DD.   +16 more
europepmc   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

Baseline and On-Treatment Absolute Lymphocyte Count-Defined Lymphopenia in Solid Tumors Treated With Immune Checkpoint Inhibitors: A Systematic Review With Structured Qualitative Synthesis. [PDF]

Cureus
Cherradi B, Pallandre M, Gil T, Kaikani W, Barjij I.   +4 more
europepmc   +1 more source

Preoperative low absolute lymphocyte count to fibrinogen ratio correlated with poor survival in nonmetastatic colorectal cancer. [PDF]

World J Surg Oncol, 2022
Huang X, Huan Y, Liu L, Ye Q, Guo J, Yan B.   +5 more
europepmc   +1 more source

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

BMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu, Hang Yao, Zhen Zhang, Zhonglian Wu, Huiqun Zhou, Bangheng Liu, Liang Ma, Yulei Mu, Dong‐An Wang   +8 more
wiley   +1 more source

Impact of absolute lymphocyte count upon admission to ICU on 28-day mortality in sepsis patients in ICU. [PDF]

Front Immunol
Zhong D, Zhao L.
europepmc   +1 more source