Results 181 to 190 of about 1,308,562 (279)

Absolute lymphocyte count recovery following initial acute myelogenous leukemia therapy: Implications for adoptive cell therapy. [PDF]

Pediatr Blood Cancer, 2023
Molina JC, Li Y, Otto WR, Miller TP, Getz KD, Mccoubrey C, Ramos M, Krause E, Cao L, Gramatges MM, Rabin K, Scheurer M, Elgarten CW, Myers RM, Seif AE, Fisher BT, Shah NN, Aplenc R.   +17 more
europepmc   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source

Tumor Necrosis Factor Inhibitor Therapy Increases Absolute Lymphocyte Count and Is Associated With Lower Mortality in Patients With Psoriatic Arthritis. [PDF]

ACR Open Rheumatol
Kostadinova L, Wilson B, Siddiqui H, Behrens S, Gupta A, O'Mara M, Brittlebank J, Nahra V, Makandura M, Malakooti SK, Hall E, Silversteyn L, Shive CL, Mattar M, Zidar DA, Anthony DD.   +15 more
europepmc   +1 more source

Constructing an External Control Arm Using the French REALYSA Cohort to Replicate Outcomes of a Randomized Trial Arm in Advanced Hodgkin Lymphoma

Clinical Pharmacology &Therapeutics, EarlyView.
External control (EC) arms using routine data can be used as comparators in clinical trials under certain conditions. The objective of this study was to assess the ability of an EC arm to replicate outcomes of a randomized controlled trial (RCT) arm receiving the same treatment strategy in advanced stage classical Hodgkin lymphoma and serve as ...
Olivia Febvey‐Combes, Cédric Rossi, Behrouz Kassai, Tesla Murairi Mirimo, Loïc Chartier, Fanny Cherblanc, Emeline Cugnod, Hervé Ghesquières, Aurélien Belot   +8 more
wiley   +1 more source

Absolute lymphocyte count trajectory predicts clinical outcome in severely injured patients. [PDF]

Eur J Trauma Emerg Surg
Reichardt LM, Hindelang B, Süberkrüb L, Hamberger KL, Graw JA, Schuetze K, Zechendorf E, Mannes M, Halbgebauer R, Wohlgemuth L, Wohlgemuth L, Gebhard F, Huber-Lang M, Relja B, Bergmann CB.   +14 more
europepmc   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Low Absolute Lymphocyte Count Associated With Anti-Thymocyte Globulin Induction May Be a Predictor of Early Cytomegalovirus Infection in Pediatric Heart Transplantation. [PDF]

Pediatr Transplant
Chan A, Tan R, Tan S, Kuhn M, Shwaish N, Chinnock R, Tran H, Frandsen E.   +7 more
europepmc   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

Prognostic value of absolute lymphocyte count in patients with advanced esophageal cancer treated with immunotherapy: a retrospective analysis. [PDF]

Ann Transl Med, 2022
Zhao Q, Bi Y, Xue J, Liu Y, Zhu J, Qin S.   +5 more
europepmc   +1 more source

Automated B‐cell and plasma cell identification using unsupervised clustering by FlowSOM and an excel‐based classification model

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Manual gating for plasma cell (PC) identification in multiparametric flow cytometry (MFC) is time‐consuming and operator‐dependent, especially when PCs are scarce. Artificial intelligence approaches such as unsupervised clustering (e.g., FlowSOM) map high‐dimensional data that still require expert interpretation.
Ethan James Gantana, Ernest Musekwa, Erica‐Mari Nell, Zivanai Cuthbert Chapanduka   +3 more
wiley   +1 more source