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Predicting Failure at Initiation of High‐Flow Nasal Oxygen in Patients With COVID‐19: Literature Review, Development and Internal Validation of a Prediction Model
Respirology, EarlyView.A prediction model was developed for high‐flow nasal oxygen (HFNO) failure in acute hypoxemic patients with COVID‐19 pneumonia using predictors available prior to HFNO initiation. This stable and good‐performing model can assist in clinical decision‐making at a critical point, aiding timely intervention for patients at risk of HFNO failure.Daphne J. T. Sjauw, Matthijs L. Janssen, Yasemin Türk, Carmen A. T. Reep, Leo Heunks, Sara J. Baart, Evert‐Jan Wils, on behalf of the Dutch HFNO study group, NORMO2 project group, E. J. Wils, H. Endeman, W. Hanselaar, M. L. Janssen, Y. Türk, R. A. S. Hoek, R. Heller, D. P. Boer, J. H. Elderman, A. Dubois, O. Hoiting, J. Holters, M. vd Steen‐Dieperink, L. Heunks, E. J. Wils, S. J. Baart, M. L. Duiverman, L. M. Fleuren, L. C. Urlings‐Strop, J. G. van den Aardweg, D. Weller, C. A. T. Reep, D. J. T. Sjauw +31 morewiley +1 more sourceBaseline Neutrophil‐To‐Lymphocyte Ratio as a Risk Stratification Marker for Severe Checkpoint Inhibitor Pneumonitis in Patients With Non‐Small Cell Lung Cancer: A Two‐Cohort Study With Retrospective Discovery and Prospective Validation
Respirology, EarlyView.The association between baseline neutrophil‐to‐lymphocyte ratio (NLR) and severe checkpoint inhibitor pneumonitis (CIP) was analyzed in discovery retrospective and validation prospective cohorts. Higher baseline NLR (≥ 4.75) was associated with increased severe CIP incidence in both cohorts.Tetsu Hirakawa, Kakuhiro Yamaguchi, Shun Takao, Nobuhiro Kanaji, Naoko Matsumoto, Kozue Miyazaki, Tamio Okimoto, Chihiro Ando, Hisao Higo, Masaaki Yanai, Koji Kurose, Yasunari Nagasaki, Masako Watanabe, Kosuke Oyama, Yuko Toyoda, Yoshihiro Taguchi, Shimpei Tada, Kiyofumi Shimoji, Shinjiro Sakamoto, Yasushi Horimasu, Takeshi Masuda, Taku Nakashima, Hiroshi Iwamoto, Hironobu Hamada, Noboru Hattori +24 morewiley +1 more sourceSome of the next articles are maybe not open access.Related searches: