Results 261 to 270 of about 175,779 (327)

Transcriptomic Analysis of Allergic Patch Test Reactions in Non‐Atopic Patients: A Comparative Study Across Multiple Allergens

open access: yesAllergy, EarlyView.
This study investigated the immune mechanisms underlying allergic contact dermatitis (ACD) in response to four distinct allergens by using RNA sequencing in a cohort of 40 non‐atopic patients and 19 controls. A shared ACD imprinting across allergens showed strong innate and adaptive responses, dominated by type 1 immunity but with mixed immune ...
David Pesqué   +9 more
wiley   +1 more source

Venetoclax-Based Regimens in CLL: Immunoglobulin G Levels, Absolute Neutrophil Counts, and Infectious Complications

open access: gold
Wojciech Szlasa   +12 more
openalex   +1 more source

Impact of age at first visit on glycolipid metabolism, bone metabolism, and fertility potential in patients with Klinefelter syndrome

open access: yesAndrology, EarlyView.
Abstract Background Classic Klinefelter syndrome (KS) is characterized by one extra X chromosome (47, XXY), leading to hypergonadotropic hypogonadism and higher risk of alterations in glycolipid homeostasis, cardiovascular diseases, and low bone mineral density. Most frequently, KS is diagnosed in adulthood because of infertility.
Giordana Ferraioli   +7 more
wiley   +1 more source

Postoperative inflammatory responses and association with in‐hospital mortality after general surgery

open access: yesANZ Journal of Surgery, EarlyView.
Abstract Background The relationship between postoperative in‐hospital mortality and inflammatory markers has not been well described. This study aimed to characterize the association between specific clinical markers of inflammation and in‐hospital mortality in the early postoperative period in general surgical patients.
Joshua G. Kovoor   +10 more
wiley   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Acute Immune Cell Dynamics During Myocardial Infarction and Their Association with Mortality. [PDF]

open access: yesInt J Mol Sci
Avgousti H   +5 more
europepmc   +1 more source

Younger Age and Viral Triggers Were Associated With Post‐Infectious Bronchiolitis Obliterans in French Children

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Post‐infectious bronchiolitis obliterans (PIBO) is a rare but severe chronic paediatric obstructive lung disease, characterised by the obliteration of small airways following severe lower respiratory tract infections. Epidemiological data in Europe remain limited. Methods This multicentre retrospective study examined the characteristics of
Julie Mazenq   +24 more
wiley   +1 more source

Accuracy of Inflammatory Biomarkers for Ruling out Invasive Bacterial Infections in Young Febrile Infants

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To investigate the diagnostic accuracy of procalcitonin (PCT), C‐reactive protein (CRP) and absolute neutrophil count (ANC) to rule out invasive bacterial infections (IBI) in well‐appearing febrile infants aged ≤ 60 days. Methods Multicentre study of infants ≤ 60 days with fever without source.
Ebba Nordström Carlsson   +2 more
wiley   +1 more source

Can we identify individuals at risk to develop multiple myeloma? A machine learning‐based predictive model

open access: yesBritish Journal of Haematology, EarlyView.
Individuals who may develop multiple myeloma within 5 years. Stage I (left) identifies patient and control groups and variables that differ between them. Stage II (middle) develops a complex SGBOOST model to predict future MM patients. Stage III (right) develops a simplified model.
Moshe Mittelman   +8 more
wiley   +1 more source

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