Results 261 to 270 of about 187,835 (334)

The Evolution of Pneumocystis jirovecii Pneumonia Prophylaxis for Pediatric Patients With Extracranial Solid Tumors: A Review of Historical Insights and Future Directions

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Association of UGT1A1 phenotype with absolute neutrophil count during irinotecan-based chemotherapy.

Natthakul Akarapredee (22837754), Chalirmporn Atasilp (17339917), Chonlaphat Sukasem (2794669), Pimonpan Jinda (10723086), Rattanaporn Sukprasong (9609323), Jiraporn Jensuriyarkun (22837757), Soravit Wongjitjanyong (22837760), Patompong Satapornpong (18432271), Natchaya Vanwong (9609311)   +8 more
openalex   +1 more source

Evaluation of Absolute Neutrophil, Lymphocyte and Platelet Count and Their Ratios as Predictors of Thrombotic Risk in Patients with Prefibrotic and Overt Myelofibrosis [PDF]

Marko Lucijanić, Ivan Krečak, Ena Sorić, Anica Sabljić, Davor Galušić, Hrvoje Holik, Vlatka Periša, Martina Morić Perić, Ivan Zekanović, Josipa Budimir, Rajko Kušec   +10 more
openalex   +1 more source

C‐Reactive Protein and Neutrophil‐To‐Lymphocyte Ratio: Can They Be Used Interchangeably in Tracking Clozapine‐Related Inflammation?

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
ABSTRACT Background Clozapine initiation often triggers inflammatory responses that can alter metabolism via Cytochrome P450 1A2 (CYP1A2) suppression. Although C‐reactive protein (CRP) is the recommended marker, it may be unavailable in community settings.
Nicoline Bihelek, Chad A. Bousman, William G. Honer, Reza Rafizadeh   +3 more
wiley   +1 more source

Life-Threatening Agranulocytosis Induced by Sinomenine Hydrochloride in Chronic Kidney Disease: A Case Report and Literature Review. [PDF]

Clin Case Rep
Xin P, Liu R, Zhang Y, Fu B.
europepmc   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

Paraneoplastic Leukemoid Reaction in Lung Adenocarcinoma With Multi-lineage Granulocytic Abnormalities and Eosinophilic Pleural Effusion. [PDF]

Cureus
Duan Y, Yang Y, Yu H, Zhang C, Wang Y, Ruan M, Yunyan Z.   +6 more
europepmc   +1 more source

Absolute neutrophil count (ANC) and adverse drug reaction (ADR) monitoring during clozapine treatment: a global Delphi guideline

D. Siskind
openalex   +1 more source

Long‐term remission in gout: Challenges and future opportunities

Rheumatology &Autoimmunity, EarlyView.
Prolonged hyperuricemia is a major risk factor for gout, which is now regarded as a curable disease. Awareness of the various factors that can trigger gout flares is essential for their prevention. An important determinant of treatment decisions and long‐term follow‐up is the quality of the clinician–patient relationship. The “treat‐to‐target” approach
Patapong Towiwat, Zhanguo Li
wiley   +1 more source