Clinical management of CMML—State of the art
Patients with chronic myelomonocytic leukaemia (CMML) typically present with clinical feature including splenomegaly, constitutional symptoms and autoimmune phenomena, as well as with pathological blood counts and biological features in the marrow. These characteristics may influence the assignment to prognostic categories such as the CPSSmol and also ...
K. Nachtkamp+3 more
wiley +1 more source
Incidence and Outcomes of Neutropenic Enterocolitis Post-stem Cell Transplant for Hematological Malignancies: A Retrospective Study in Australia. [PDF]
Francis S.
europepmc +1 more source
Prevalence of myeloid gene alterations in paediatric cutaneous and systemic mastocytosis
A total of 69 children with paediatric mastocytosis, including cutaneous and systemic subtypes, were enrolled in a prospective natural history study (NCT00044122). They underwent next‐generation sequencing of peripheral blood to assess myeloid gene alterations.
Xiaoping Sun+4 more
wiley +1 more source
Sequencing of chemotherapy in total neoadjuvant treatment for rectal cancer does not predict radiation-induced lymphopenia. [PDF]
Orazem M, Velenik V, Ihan A.
europepmc +1 more source
Summary Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, life‐threatening disorder characterized by complement‐mediated haemolysis, leading to anaemia and thrombosis. HRS‐5965 is a novel, oral, selective complement factor B inhibitor targeting the alternative pathway, potentially reducing both intra‐ and extravascular haemolysis.
Li Zhang+7 more
wiley +1 more source
Management of Graves Disease With Co-Existing Duffy-Null Phenotype. [PDF]
Ferri GM+5 more
europepmc +1 more source
Summary Clinical outcome after chimeric antigen receptor (CAR)‐T‐cell failure in large B‐cell lymphoma (LBCL) is dismal. Allogeneic stem cell transplantation (alloSCT) represents a potentially curative salvage for relapsed/refractory LBCL, although concerns remain regarding its feasibility and safety in patients exposed to CAR‐T and bispecific ...
Angelica Barone+10 more
wiley +1 more source
Comorbidity patterns and immune-metabolic differences in patients with acute-episode of schizophrenia spectrum disorders. [PDF]
Wu G+14 more
europepmc +1 more source
Variations in haematological and inflammatory biomarkers and their association with Plasmodium falciparum malaria: a cross-sectional comparative study at a clinic in Ghana. [PDF]
Bohli JK+9 more
europepmc +1 more source
A multi pronged analysis approach revealed distinct neoplastic populations in PA and GG. Non‐neoplastic populations in PA showed higher levels of immune mobilizing chemokines in PA compared to GG. Abstract Pediatric low‐grade gliomas (pLGG) comprise 35% of all brain tumors.
Shadi Zahedi+19 more
wiley +1 more source