Results 271 to 280 of about 187,835 (334)

Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma [PDF]

open access: yes, 2018
Belt, Brian A   +14 more
core   +1 more source

Identification of Clinically Distinct Clusters in Patients With Severe COPD Using Circulating Blood Cell Population Parameters

open access: yesRespirology, EarlyView.
This study investigated whether blood cell population data, in addition to cell counts, can identify clinically relevant COPD subgroups. Four distinct inflammatory profiles were identified with distinct clinical characteristics. Cell population data have the potential to provide additional insights beyond inflammatory cell counts and improve patient ...
Pauline J. M. Kuks   +6 more
wiley   +1 more source

Clinical outcomes of immunosuppressive therapy for severe aplastic anemia patients with absolute neutrophil count of zero

open access: gold, 2019
Jia Liu   +8 more
openalex   +1 more source

Associations of Vestibular Disorders With Risk of All‐Cause and Cause‐Specific Dementia: A Longitudinal Cohort Study in UK Biobank

open access: yesSensory Neuroscience, EarlyView.
ABSTRACT To explore associations of vestibular disorders with all‐cause and cause‐specific dementia and underlying biological mechanisms/neuroimaging changes. A population‐based cohort study of 406,348 UK Biobank participants was conducted. Inverse probability of treatment weighting (IPTW) balanced baseline covariates, and Cox proportional hazards ...
Xiaofei Li   +15 more
wiley   +1 more source

Correlation analysis between sleep quality and cardiac function indicators in patients with chronic heart failure

open access: yesSleep Research, EarlyView.
Abstract Objective To assess sleep quality and its influencing factors in patients with chronic heart failure (CHF). Methods A study of 112 CHF patients was conducted using the Pittsburgh Sleep Quality Index (PSQI). Clinical and socio‐demographic data were collected.
Meng‐Dan Chu   +6 more
wiley   +1 more source

Efficiency comparison between new single‐needle dialysis and conventional double‐needle dialysis and exploration of the optimal prescription parameters for single‐needle hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, Volume 29, Issue 3, Page 419-427, June 2025.
Abstract Objective To compare the dialysis efficiency parameters between new single‐needle dialysis and conventional double‐needle dialysis and to explore the optimal prescription parameters for single‐needle hemodialysis. Methods This study involved a prospective, cross‐over design. Eight patients were randomly divided into two cohorts, which received
Bin Zhao   +8 more
wiley   +1 more source

CXCR4 antagonism corrects neutrophil abnormalities and reduces pneumonia severity in a pharmacological mouse model of CXCR2 loss-of-function-mediated neutropenia. [PDF]

open access: yesFront Immunol
Nguyen CH   +8 more
europepmc   +1 more source

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

open access: yesAllergy, EarlyView.
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong   +217 more
wiley   +1 more source

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