Results 281 to 290 of about 175,779 (327)

The Black Hole of Immune Checkpoint Blocking Therapy for Gastric Cancer: Hyperprogressive Disease

open access: yesCancer Science, EarlyView.
This review summarizes the mechanisms, predictive biomarkers, prevention, and treatment methods of HPD after immune checkpoint blockade therapy, providing a theoretical basis for making a judgment on the efficacy of ICI treatment for gastric cancer.
Zhuan‐Fang Wang   +7 more
wiley   +1 more source

Prognostic significance of the pan-immune-inflammation value (PIV) in patients with differentiated thyroid carcinoma. [PDF]

open access: yesArch Endocrinol Metab
Öztürk Y   +4 more
europepmc   +1 more source

Mucopolysaccharidosis Type IIIB With Pancytopenia: A Case Report and Hematological Correlations in Mice

open access: yesClinical Genetics, EarlyView.
We report an individual with mucopolysaccharidosis type IIIB and chronic pancytopenia. Hematological studies in a mouse model revealed microcytic anemia and decreased monocyte count. Hence, pancytopenia is thought to be secondary to mucopolysaccharidosis type IIIB, and we suggest that a complete blood count should be included in the clinical ...
Éliane Beauregard‐Lacroix   +3 more
wiley   +1 more source

PCSK9 and coronary atherosclerosis progression beyond LDL‐cholesterol in coronary artery disease patients

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
In a population of patients with stable CAD, circulating levels of PCSK9 are independently associated with the progression of adverse coronary plaque phenotypes, as assessed by serial coronary computed tomography angiography. At RNA‐seq analysis of whole blood, PCSK9 was linked to the expression of genes involved in the innate‐immune response.
Rosetta Ragusa   +7 more
wiley   +1 more source

HLA epitope mismatch in haploidentical transplantation is associated with decreased relapse and delayed engraftment [PDF]

open access: yes, 2018
DiPersio, John F.   +6 more
core   +1 more source

Epileptogenesis in meningioma: Theories, putative biomarkers, and postoperative risk

open access: yesEpilepsia, EarlyView.
Abstract Cranial meningioma are the most common type of primary brain tumor, and focal onset, tumor‐related seizures affect a significant proportion of patients. Seizures affect 30% of symptomatic preoperative patients and a further 12% of postoperative patients.
William H. Cook   +5 more
wiley   +1 more source

Acute hepatitis and haemolysis associated with doxycycline and rifampin administration in two weanling foals

open access: yesEquine Veterinary Education, EarlyView.
Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock   +7 more
wiley   +1 more source

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