Results 71 to 80 of about 92,541 (304)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Diagnostic value of neutrophil lymphocyte ratio in detection of acute appendicitis
Background: The diagnosis of acute appendicitis (AA) sometimes is illusive and the accompanying clinical and laboratory manifestations cannot be used for definitive diagnosis.
Istabraq Akram Al-Husseiny
doaj +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Critical pertussis: A multi-centric analysis of risk factors and outcomes in Oman
Objectives: To identify risk factors and outcomes of patients with critical pertussis. Design: Retrospective observational cohort study. Setting: Sultan Qaboos University Hospital and The Royal Hospital, Muscat, Oman. Subjects: Children aged
Florence Birru+5 more
doaj
BackgroundsThe goal of this study was to assess the impact of neutrophil count, in patients with acute type A aortic dissection (ATAAD).MethodsThis study retrospectively collected data from patients between September 2017 and June 2021.
Weiqi Feng+9 more
doaj +1 more source
Hubungan Jumlah Neutrofil Absolut dengan Mortalitas pad Stroke Iskemik Akut dengan Komplikasi Pneumonia [PDF]
Background: Acute ischemic stroke patients with pneumonia experienced inflammation reaction which induces neutrophil invasion to lung tissue as a defense mechanism towards infection.
Sariningsih, Sariningsih
core
Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia [PDF]
Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in malaria-endemic sub-Saharan Africa, where the greatest sickle-cell burden exists, remain unknown.
Hodges, James S.+8 more
core +2 more sources
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
Introduction. The virulence factors from community acquired-methicillin resistant Staphylococcus aureus (CA-MRSA) mainly due to toxins like Panton Valentin Leukocidin (PVL) and Phenol Soluble Modulin (PSM).
Kurniyanto+3 more
doaj +1 more source
Abstract Background The detrimental effect of leukocytosis on survival in myeloproliferative neoplasms (MPN) has been well established for primary myelofibrosis (PMF), polycythemia vera (PV) and essential thrombocythemia (ET ) (JCO. 2018;36:310; BJH.
Curtis A. Hanson+11 more
openaire +2 more sources