Results 101 to 110 of about 1,495,761 (300)

Metal implants influence CT scan parameters leading to increased local radiation exposure: A proposal for correction techniques.

PLoS ONE, 2019
Metal implants not only deteriorate image quality, but also increase radiation exposure. The purpose of this study was to evaluate the effect of metal hip prosthesis on absorbed radiation dose and assess the efficacy of organ dose modulation (ODM) and ...
Ok Kyu Song, Yong Eun Chung, Nieun Seo, Song-Ee Baek, Jin-Young Choi, Mi-Suk Park, Myeong-Jin Kim   +6 more
doaj   +1 more source

Radiation sensitive medium for recording an absorbed dose distribution [PDF]

, 2017
The invention relates to a radiation sensitive medium for recording an absorbed dose distribution from an external radiation source such as e.g. a linear particle accelerator used for e.g. cancer treatment or radiation processing.
Andersern, Claus Erik, Lindvold, Lars René, Helt-Hansen, Jakob, Miller, Arne   +3 more
core  

A new dose index in mammography: innovative experimental method to assess the average absorbed breast dose

, 2018
Breast cancer is the principal cause of death from cancer among women worldwide. Nevertheless, early detection of breast cancer through adequate screening programs can save many lives, reducing the overall mortality.
P. Barca, A. C. Traino, D. Caramella, C. Sottocornola, C. Marini, M. E. Fantacci, G. Aringhieri   +6 more
core   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

An international study of factors affecting variability of dosimetry calculations, part 5: impact of segmentation methods

EJNMMI Physics
Background Individualized radiopharmaceutical therapies guided by patient-specific absorbed dose assessments using imaging have the potential to improve both efficacy and safety.
Sara Kurkowska, Yuni K. Dewaraja, Eric C. Frey, Julia Brosch-Lenz, John Sunderland, Carlos Uribe   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

In vivo dosimetry for head and neck carcinoma: determination of target absorbed dose from entrance and exit absorbed dose measurements

, 2011
The aims of this work were to measure the entrance and exit dose for patient treated for head and neck tumors. The target absorbed dose was determined from the exit and entrance dose measurement. Twenty patients were evaluated.
M. Besbes, A. Bridier, J. Daoud, L. Farhat   +3 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source