Results 51 to 60 of about 1,495,761 (300)
EJNMMI Research, 2017 Background To date, the estimated radiation-absorbed dose to organs and tissues in patients undergoing diagnostic examinations in nuclear medicine is derived via calculations based on models of the human body and the biokinetic behaviour of the ...
Martin Andersson +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Egyptian Journal of Radiology and Nuclear Medicine, 2016 Purpose: Study of absorbed dose in the heart, breast, stomach, lungs, thyroid, kidney, and liver during CT scan of the chest at different tube voltages using Medical Internal Radiation Dose (MIRD) phantom and MCNP code at values of tube voltage 80 kVp ...
Tawfik Abo Shdeed +3 more
doaj +1 more source
The MIRD method of estimating absorbed dose [PDF]
, 1991 The estimate of absorbed radiation dose from internal emitters provides the information required to assess the radiation risk associated with the administration of radiopharmaceuticals for medical applications.
Weber, D.A.
core
Absorbed dose, equivalent dose, measured dose rates, and implications for OSL age estimates: Introducing the Average Dose Model [PDF]
, 2017 Luminescence ages are calculated by dividing an absorbed dose by the dose rate to which the natural dosimeter has been exposed. In practice, one measures an equivalent dose, De; in the absence of an alpha dose contribution, this should be ...
Kreutzer, S. +28 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Absorbed dose thresholds and absorbed dose rate limitations for studies of electron radiation effects on polyetherimides [PDF]
, 1989 The threshold values of total absorbed dose for causing changes in tensile properties of a polyetherimide film and the limitations of the absorbed dose rate for accelerated-exposure evaluation of the effects of electron radiation in geosynchronous orbit ...
Long, Edward R., Jr. +3 more
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source