Results 151 to 160 of about 85,471 (316)
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Fourier spectra of resonant nuclear forward scattering: lineshape dependence on absorber thickness ...
王军虎, K. Nomura, A. I. Rykov
core
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Impact Vibration Absorber of Pendulum Type
In this paper the impact vibration absorber of pendulum type is examined using numerical simulation. Pendulum vibration absorbers are widely used in practice. It consists of pendulum impact mass with motion limiting stops attached to the vibrating system.
Sokolova, Svetlana +2 more
core
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Machine learning for metasurfaces broadband absorber design
Metasurfaces have been emerging increasingly due to their realization of various technologies in meeting the design of multi-functional, compact, highly efficient, tunable, and low-cost designs owing to the fact that they can manipulate electromagnetic ...
Ijaz, Sumbel +5 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Study on a Novel Absorption Referigeration System at Low Cooling Temperatures
A novel absorption refrigeration system is proposed in this context using R134a+R23 mixed refrigerants and DMF solvent. The new system uses two-staged absorber in series to reduce the evaporation pressure and can obtain a lower refrigeration temperature ...
Chen, Guangming +3 more
core
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source

