Results 101 to 110 of about 446,195 (288)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Weakly Compact Uniform Attractor for the Nonautonomous Long-Short Wave Equations
Abstract and Applied Analysis, 2013 Solutions and weakly compact uniform attractor for the nonautonomous long-short wave equations with translation compact forces were studied in a bounded domain.
Hongyong Cui, Jie Xin, Anran Li
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Reconstruction of discrete sets from two absorbed projections: an algorithm
Electronic Notes in Discrete Mathematics, 2003 Abstract Two left and right horizontal absorbed projections along a single direction uniquely determine a row of a binary matrix. After proving this result we give a polynomial time algorithm which reconstructs such a row and we analyze its performances by determining the worst case complexity.
BARCUCCI, ELENA +2 more
openaire +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Jixie qiangdu, 2023 In order to ensure the secondary part at the front end of vehicles absorb the impact energy as much as possible in case of collision, reduce the impact on main parts, and ensure the safety of passengers and drivers, the energy absorption structure is set
LIU ZhaoXin, LI YongKuan, XIA DongWei
doaj
Normal systems over ANR’s, rigid embeddings and nonseparable absorbing sets [PDF]
Acta Mathematica Sinica, English Series, 2012 26 ...
openaire +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Preparation and properties of Mg-Nd binary alloy MAO/SiO2@α-Fe2O3 organic composite coating
npj Materials DegradationIn order to make magnesium alloys better used in aviation, electronic information and other fields, it is necessary to improve their corrosion resistance and wave absorption properties.
Qiang Sun +8 more
doaj +1 more source