Results 91 to 100 of about 5,052,521 (413)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Self‐Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?

Advanced Science, 2019
Given their durability and long‐term stability, self‐healable hydrogels have, in the past few years, emerged as promising replacements for the many brittle hydrogels currently being used in preclinical or clinical trials. To this end, the incompatibility
Sepehr Talebian, Mehdi Mehrali, Nayere Taebnia, Cristian Pablo Pennisi, Firoz Babu Kadumudi, Javad Foroughi, Masoud Hasany, Mehdi Nikkhah, Mohsen Akbari, Gorka Orive, Alireza Dolatshahi‐Pirouz   +10 more
doaj   +1 more source

Theory of amplification of sound (acoustic phonons) by absorption of laser radiation in quantum wires with parabolic potential [PDF]

arXiv, 2002
Based on the quantum transport equation for the electron-phonon system, the absorption coefficient of sound (acoustic phonons) by absorption of a laser radiation in quantum wires with parabolic potential is calculated for the case of monophoton absorption and the case of multiphoton absorption.
arxiv  

A catalogue of absorption-line systems in QSO spectra

, 2003
We present a new catalog of absprption-line systems identified in the quasar spectra. It contains data on 821 QSOs and 8558 absorption systems comprizing 16139 absorption lines with measured redshifts in the QSO spectra.
A. D. Kaminker, A. I. Ryabinkov, Curran, D. A. Varshalovich, Ellis, Hewitt, Hewitt, Hewitt, Hewitt, Junkkarinen, Kaminker, Outram, Perry, Ryabinkov, Ryabinkov, Veron-Cetty, York   +16 more
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

On the amplification of sound (acoustic phonons) by absorption of laser radiation in cylindrical quantum wires [PDF]

arXiv, 2002
Based on the quantum transport equation for the electron-phonon system, the absorption coefficient of sound (acoustic phonons) by absorption of laser radiation in cylindrical quantum wires is calculated for the case of monophoton absorption process and the case of multiphoton absorption process.
arxiv  

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Absorption by Spinning Dust: a Contaminant for High-Redshift 21 cm Observations

, 2018
Spinning dust grains in front of the bright Galactic synchrotron background can produce a weak absorption signal that could affect measurements of high redshift 21 cm absorption.
Draine, B. T., Miralda-Escudé, Jordi
core   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Sensitivity of p-mode absorption on magnetic region properties and kernel functions

, 2011
Aims. Magnetohydrodynamic (MHD) sausage tube waves are excited in magnetic flux tubes by p-mode forcing. These tube waves carry energy away from the p-mode cavity which results in a source of absorption.
Gascoyne, A., Hindman, B.W., Jain, R.
core   +1 more source