Results 71 to 80 of about 3,511,004 (300)

The measurement of ionospheric absorption using extraterrestrial radio waves [PDF]

open access: yes, 1957
Introduction: The discovery by Jansky in 1932 of the presence of radio waves incident upon the earth from outer space has led to several new methods of studying the earth's upper atmosphere.
Little, C. G.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Detection of OH absorption against PSR B1849+00

open access: yes, 2003
We have searched for OH absorption against seven pulsars using the Arecibo telescope. In both OH mainlines (at 1665 and 1667 MHz), deep and narrow absorption features were detected toward PSR B1849+00. In addition, we have detected several absorption and
Abigail Hedden   +17 more
core   +1 more source

Discovery of Broad Soft X-ray Absorption Lines from the Quasar Wind in PDS 456 [PDF]

open access: yes, 2016
High resolution soft X-ray spectroscopy of the prototype accretion disk wind quasar, PDS 456, is presented. Here, the XMM-Newton RGS spectra are analyzed from the large 2013-2014 XMM-Newton campaign, consisting of 5 observations of approximately 100 ks ...
Behar, Ehud   +7 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Transmission, reflection and localization in a random medium with absorption or gain

open access: yes, 2005
We study reflection and transmission of waves in a random tight-binding system with absorption or gain for weak disorder, using a scattering matrix formalism.
Anderson P W   +8 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The effect of black tea and water temperature on the disintegration of gelatine and HPMC capsules, tested with the paddle device, GastroDuo and in vivo pharmacokinetics: Much ado about little

open access: yesInternational Journal of Pharmaceutics: X
Fluid co-administered with oral medication directly affects its behaviour. Often, people use fluids other than water when taking their medications. Capsules (mainly gelatine- and HPMC-based) are widely used solid oral dosage forms.
Dorota Sarwinska   +11 more
doaj   +1 more source

Self‐Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?

open access: yesAdvanced Science, 2019
Given their durability and long‐term stability, self‐healable hydrogels have, in the past few years, emerged as promising replacements for the many brittle hydrogels currently being used in preclinical or clinical trials. To this end, the incompatibility
Sepehr Talebian   +10 more
doaj   +1 more source

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