Results 21 to 30 of about 3,631,195 (345)
Frontiers in Pharmacology, 2021 Genome-wide association studies have identified an association between isobutyrylcarnitine (IBC) and organic cation transporter 1 (OCT1) genotypes. Higher IBC blood concentrations in humans with active OCT1 genotypes and experimental studies with mouse ...
Ole Jensen +5 more
doaj +1 more source
Starfruit Leaves as Glucose Absorption Inhibitor in Mice's Small Intestinal Epithelial Cells [PDF]
, 2016 Background: Starfruit (Averrhoa carambola) leaves contain flavone derivatives that exhibit anti-hyperglycemic effects. This study aims to determine the effect of starfruit leaves in reducing glucose absorption in intestinal epithelial cells of mice ...
Dewanto, J. B. (Julius) +2 more
core +1 more source
Various effects of repeated rifampin dosing on coproporphyrin levels in humans
Clinical and Translational Science, 2023 In recent years, the identification of endogenous substrates as biomarkers became an uprising topic. Particularly coproporphyrins (CPs), byproducts of heme biosynthesis, are intensely investigated as biomarkers for predicting interactions with the ...
Jonny Kinzi +5 more
doaj +1 more source
Organic Cation Transporter 1 an Intestinal Uptake Transporter: Fact or Fiction?
Frontiers in Pharmacology, 2021 Intestinal transporter proteins are known to affect the pharmacokinetics and in turn the efficacy and safety of many orally administered drugs in a clinically relevant manner.
Christoph Wenzel +2 more
doaj +1 more source
Calcium Absorption—A Paradigm for Mineral Absorption [PDF]
The Journal of Nutrition, 1998 Intestinal calcium absorption proceeds by two mechanisms, an active transcellular process that takes place in the duodenum and a passive paracellular process throughout the small intestine. This article characterizes the three steps of transcellular calcium movement-entry, intracellular diffusion and extrusion-and identifies conditions that must be ...
openaire +3 more sources
Minimal Absorption Measurements [PDF]
, 2001 We show that it is not possible to discriminate two close transparencies without a certain number of photons being absorbed.
A.C. Elitzur +11 more
core +2 more sources
Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research
Pharmaceutics, 2022 Drug absorption following oral administration is determined by complex and dynamic interactions between gastrointestinal (GI) physiology, the drug, and its formulation.
Stefan Senekowitsch +15 more
doaj +1 more source
Transmission channels for light in absorbing random media: from diffusive to ballistic-like transport [PDF]
, 2014 While the absorption of light is ubiquitous in nature and in applications, the question remains how absorption modifies the transmission channels in random media.
Cao, Hui +4 more
core +2 more sources
Frontiers in Bioengineering and Biotechnology, 2022 Exogenous glucocorticoids increase the risk for osteoporosis, but the role of endogenous glucocorticoids remains elusive. Here, we describe the generation and validation of a loss- and a gain-of-function model of the cortisol producing enzyme 11β-HSD1 ...
Angelique Kragl +10 more
doaj +1 more source
Glycerol gelatin for 3D-printing of implants using a paste extrusion technique
Current Directions in Biomedical Engineering, 2017 Fused deposition modeling as an additive manufacturing technique has gained great popularity for the fabrication of medical devices as well as pharmaceutical dosage forms over the last years.
Kempin Wiebke +3 more
doaj +1 more source