Results 71 to 80 of about 5,169,045 (382)
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Transmission, reflection and localization in a random medium with absorption or gain
, 2005 We study reflection and transmission of waves in a random tight-binding system with absorption or gain for weak disorder, using a scattering matrix formalism.
Anderson P W +8 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Quantification of nonlinear absorption in ternary As-Sb-Se chalcogenide glasses
, 2018 In this article, we studied intensity dependent third order nonlinear optical response in ternary As40Sb7Se53 and As40Sb10Se50 chalcogenide glasses by employing nanosecond Z-scan technique.
Adarsh, K. V. +6 more
core +1 more source
Absorption cross section in de Sitter space [PDF]
, 2002 We study the wave equation for a minimally coupled massive scalar in three-dimensional de Sitter space. We compute the absorption cross section to investigate its cosmological horizon in the southern diamond.
Fischler W. +3 more
core +2 more sources
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Fermionic greybody factors of two and five-dimensional dilatonic black holes [PDF]
, 2014 We study fermionic perturbations in the background of a two and five-dimensional dilatonic black holes. Then, we compute the reflection and transmission coefficients and the absorption cross section for fermionic fields, and we show numerically that the ...
Becar, Ramón +2 more
core +2 more sources
Self‐Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?
Advanced Science, 2019 Given their durability and long‐term stability, self‐healable hydrogels have, in the past few years, emerged as promising replacements for the many brittle hydrogels currently being used in preclinical or clinical trials. To this end, the incompatibility
Sepehr Talebian +10 more
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Enhanced squeezing by absorption
, 2016 Absorption is usually expected to be detrimental to quantum coherence effects. However, the situation for complex absorption spectra has been little studied yet. We consider the resonance fluorescence of excitons in a semiconductor quantum well.
Grünwald, P., Vogel, W.
core +1 more source