Results 71 to 80 of about 3,830,075 (379)

Predicting theater chair absorption from reverberation chamber measurements - comment [PDF]

, 1993
The relationship between the measured acoustic absorption coefficient of an array of theater chairs and the ratio of the perimeter length to plan area of the array is considered.
Davies, WJ, Lam, YW, Orlowski, RJ
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Individual use of self-medication and other remedies in COVID-19 outpatients in Western-Pomerania

Scientific Reports
We analyzed data from positively tested COVID-19 outpatients to describe self-medication with OTC drugs and use of other remedies against symptoms of SARS-CoV-2 infection.
Svea Stüdemann, Eik Schäfer, Klaus Hahnenkamp, Mladen V. Tzvetkov, Stefan Engeli   +4 more
doaj   +1 more source

Exopeptidase combination enhances the degradation of isotopically labelled gluten immunogenic peptides in humans

Frontiers in Immunology
IntroductionCeliac disease is a common autoimmune-like enteropathy caused by an aberrant response to incompletely digested dietary gluten. Gluten immunogenic peptides including the immunodominant 33-mer are thought to be resistant to proteolytic ...
Sulayman Mourabit, Sarah Römer, Erin R. Bonner, Fabian Winter, Julian Tschollar, Mladen V. Tzvetkov, Werner Weitschies, Stefan Engeli, Werner Tschollar   +8 more
doaj   +1 more source

Electro-absorption of silicene and bilayer graphene quantum dots [PDF]

, 2016
We study numerically the optical properties of low-buckled silicene and AB-stacked bilayer graphene quantum dots subjected to an external electric field, which is normal to their surface.
Abdelsalam, H., Lukyanchuk, I., Portnoi, M. E., Saroka, V. A., Talaat, M. H.   +4 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

MR imaging of model drug distribution in simulated vitreous

Current Directions in Biomedical Engineering, 2015
The in vitro and in vivo characterization of intravitreal injections plays an important role in developing innovative therapy approaches. Using the established vitreous model (VM) and eye movement system (EyeMoS) the distribution of contrast agents with ...
Stein Sandra, Simroth-Loch Christian, Langner Sönke, Hadlich Stefan, Stachs Oliver, Grabow Niels, Guthoff Rudolf, Weitschies Werner, Seidlitz Anne   +8 more
doaj   +1 more source

The Black Hole: Scatterer, Absorber and Emitter of Particles [PDF]

, 1997
Accurate and powerful computational methods developed by the author for the wave scattering by black holes allow to obtain the highly non trivial total absorption spectrum of the Black Hole.
Sanchez, N.
core   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source