Results 81 to 90 of about 4,662,502 (387)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Effect of bifurcation in physicochemical parameters on outburst hazard of coal seams [PDF]

open access: yesE3S Web of Conferences, 2019
The paper considers interaction between gas-kinetic and physicochemical parameters in coal seams, which conditions coal and gas outbursts. The laboratory and field test data on interaction between geomechanical and physicochemical processes in coal seams
Kiryaeva Tatyana
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

MR imaging of model drug distribution in simulated vitreous

open access: yesCurrent Directions in Biomedical Engineering, 2015
The in vitro and in vivo characterization of intravitreal injections plays an important role in developing innovative therapy approaches. Using the established vitreous model (VM) and eye movement system (EyeMoS) the distribution of contrast agents with ...
Stein Sandra   +8 more
doaj   +1 more source

Evidence for Photoionization Driven Broad Absorption Line Variability [PDF]

open access: yes, 2015
We present a qualitative analysis of the variability of quasar broad absorption lines using the large multi-epoch spectroscopic dataset of the Sloan Digital Sky Survey Data Release 10. We confirm that variations of absorption lines are highly coordinated
Ferland, Gary   +3 more
core   +3 more sources

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Exopeptidase combination enhances the degradation of isotopically labelled gluten immunogenic peptides in humans

open access: yesFrontiers in Immunology
IntroductionCeliac disease is a common autoimmune-like enteropathy caused by an aberrant response to incompletely digested dietary gluten. Gluten immunogenic peptides including the immunodominant 33-mer are thought to be resistant to proteolytic ...
Sulayman Mourabit   +8 more
doaj   +1 more source

Absorption of Iron [PDF]

open access: yesThe American Journal of the Medical Sciences, 1897
n ...
openaire   +2 more sources

Quantum Stochastic Absorption [PDF]

open access: yes, 1999
We report a detailed and systematic study of wave propagation through a stochastic absorbing random medium. Stochastic absorption is modeled by introducing an attenuation constant per unit length $\alpha$ in the free propagation region of the one ...
Jayannavar, A. M.   +2 more
core   +1 more source

Damped Lyman-alpha Absorption Associated with an Early-Type Galaxy at Redshift z = 0.16377

open access: yes, 1997
We report new HST and ground-based observations of a damped Lyman-alpha absorption system toward the QSO 0850+4400. The redshift of the absorption system is z = 0.163770 and the neutral hydrogen column density of the absorption system is log N = 19.81 cm*
Altan, Hakan   +10 more
core   +1 more source

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