Results 31 to 40 of about 253,865 (262)

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

absorption coefficient

open access: yes, 2014
Citation: 'absorption coefficient' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.A00037 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

Absorption coefficient estimation of thin MoS2 film using attenuation of silicon substrate Raman signal

open access: yesResults in Physics, 2019
A simple, non-destructive, and convenient method using Raman spectroscopy and Atomic Force Microscopy for extracting the absorption coefficient of MoS2 is presented.
Joon Young Kwak
doaj   +1 more source

ABSORPTION COEFFICIENTS OF AIR [PDF]

open access: yes, 1960
Abstract : Tables of integrated absorption coefficients were evaluated for high-temperature air by summation of the contributions from discrete and continuous transitions. The tables were computed for dry air in the temperature range from 1,000 deg K to 12,000 deg K, at equal energy increments of 0.25 ev (2,016.5 cm. to the -1 power), in the wavelength
R. W. Nicholls   +2 more
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Akytojo betono garso absorbcijos tyrimai/Porous concrete sound absorption investigation

open access: yesJournal of Civil Engineering and Management, 1996
Low-density porous concrete can be used as a sound absorbing material. This paper generalizes porous concrete sound absorption investigations. Porous concrete relative wave resistance modulus is longer than air wave resistance W=1 and that is why this
Antanas Laukaitis, Vytautas Lasauskas
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

On-demand prediction of low-frequency average sound absorption coefficient of underwater coating using machine learning

open access: yesResults in Engineering
This study proposes an underwater coating with sound absorption ability in the middle-to-low frequency range and establishes an acoustic theoretical model combining the equivalent medium theory and the transfer matrix method.
Nansha Gao   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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