Results 21 to 30 of about 134,239 (340)

Extinction blunts paraventricular thalamic contributions to heroin relapse

Cell Reports, 2021
Summary: Here, we use optogenetics and chemogenetics to investigate the contribution of the paraventricular thalamus (PVT) to nucleus accumbens (NAc) pathway in aversion and heroin relapse in two different heroin self-administration models in rats.
Giuseppe Giannotti, Sheng Gong, Nicholas Fayette, Jasper A. Heinsbroek, James E. Orfila, Paco S. Herson, Christopher P. Ford, Jamie Peters   +7 more
doaj   +1 more source

Abstinence Education [PDF]

The Linacre Quarterly, 2014
The American College of Pediatricians strongly endorses abstinence-until-marriage sex education and recommends adoption by all school systems in lieu of “comprehensive sex education.” This position is based on “the public health principle of primary prevention—risk avoidance in lieu of risk reduction,” upholding the “human right to the highest ...
openaire   +2 more sources

Psychometric Evaluation of the Persian Version of the Dysexecutive Questionnaire in Methamphetamine-Abstinent Individuals [PDF]

Journal of Rehabilitation Sciences and Research
Background: Methamphetamine addiction is a growing global concern associated with executive dysfunctions that negatively impact daily life. Traditional tests for assessing executive dysfunctions are often complex and time-consuming.
Majid Farhadian, Malahat Akbarfahimi, Peyman Abharian   +2 more
doaj   +1 more source

Effects of extended abstinence on cognitive functions in tramadol‐dependent patients: A cohort study

Neuropsychopharmacology Reports, 2021
Background Some pieces of the literature report impaired cognitive functioning in tramadol dependence. Whether extended abstinence improves cognitive functioning or not is not well studied.
Shehab H. Hassaan, Hossam Khalifa, Alaa M. Darwish   +2 more
doaj   +1 more source

Role of Projections between Piriform Cortex and Orbitofrontal Cortex in Relapse to Fentanyl Seeking after Palatable Food Choice-Induced Voluntary Abstinence

Journal of Neuroscience, 2020
We recently developed a rat model of relapse to drug seeking after food choice-induced voluntary abstinence. Here, we used this model to study the role of the orbitofrontal cortex (OFC) and its afferent projections in relapse to fentanyl seeking.
D. Reiner, Olivia M. Lofaro, Sarah V Applebey, Hannah Korah, M. Venniro, C. Cifani, J. Bossert, Y. Shaham   +7 more
semanticscholar   +1 more source

Nicotine but not saline self-administering or yoked control conditions produces sustained neuroadaptations in the accumbens shell

Frontiers in Molecular Neuroscience, 2023
IntroductionUsing yoked animals as the control when monitoring operant drug-self-administration is considered the golden standard. However, instrumental learning per se recruits several neurocircuits that may produce distinct or overlapping ...
Ana Domi, Ana Domi, Erika Lucente, Davide Cadeddu, Louise Adermark, Louise Adermark   +5 more
doaj   +1 more source

Abstinence-dependent dissociable central amygdala microcircuits control drug craving

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Social support promotes drug abstinence. We incorporated this cardinal feature in our community-reinforcement model using rewarding social interaction.
M. Venniro, Trinity I. Russell, Leslie A. Ramsey, Christopher T. Richie, H. Lesscher, Simone M. Giovanetti, R. Messing, Y. Shaham   +7 more
semanticscholar   +1 more source

A Novel Hierarchical LATER Process Model: Evaluating Latent Sources of Variation in Reaction Times of Adult Daily Smokers

Frontiers in Psychiatry, 2019
Reaction time data from cognitive tasks continue to be a key way to assess decision-making in various contexts to better understand addiction. The goal of this paper is twofold: to introduce a nuanced modeling approach for reaction time data and to ...
Nicole J. Roberts, Zita Oravecz, Zita Oravecz, Briana N. Sprague, Charles F. Geier   +4 more
doaj   +1 more source

Connectome-Based Prediction of Cocaine Abstinence.

American Journal of Psychiatry, 2019
OBJECTIVE: The authors sought to identify a brain-based predictor of cocaine abstinence by using connectome-based predictive modeling (CPM), a recently developed machine learning approach.
S. Yip, D. Scheinost, M. Potenza, K. Carroll   +3 more
semanticscholar   +1 more source

Social Support and Treatment Outcome in Alcohol Dependence Syndrome in Armed Forces [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Social factors play vital role in unfolding of alcohol use disorders in any given population. Several factors beyond the confines of treatment settings influence treatment outcome in alcohol dependence syndrome.
Siddharth Dixit, Vinay Singh Chauhan, Sudip Azad   +2 more
doaj   +1 more source